Title:
RECOMBINANT MICROORGANISM HAVING ABILITY TO PRODUCE POLYHYDROXYALKANOATE CONTAINING 2-HYDROXYBUTYRATE AS MONOMER, AND METHOD FOR PREPARING POLYHYDROXYALKANOATE CONTAINING 2-HYDROXYBUTYRATE AS MONOMER USING SAME
Document Type and Number:
WIPO Patent Application WO/2012/124941
Kind Code:
A3
Abstract:
The present invention relates to a polyhydroxyalkanoate containing a 2-hydroxybutyrate as a monomer, a recombinant microorganism having the ability to produce the polyhydroxyalkanoate containing the 2-hydroxybutyrate as the monomer, and a method for preparing the polyhydroxyalkanoate containing the 2-hydroxybutyrate as the monomer. The present invention can effectively provide the polyhydroxyalkanoate containing the 2-hydroxybutyrate, which is a novel biodegradable polymer, and the recombinant microorganism for producing same.
Inventors:
LEE SANG YUP (KR)
PARK SI JAE (KR)
LEE SEUNG HWAN (KR)
SONG BONG KEUN (KR)
LEE TAE WOO (KR)
PARK SI JAE (KR)
LEE SEUNG HWAN (KR)
SONG BONG KEUN (KR)
LEE TAE WOO (KR)
Application Number:
PCT/KR2012/001752
Publication Date:
December 27, 2012
Filing Date:
March 09, 2012
Export Citation:
Assignee:
KOREA ADVANCED INST SCI & TECH (KR)
KOREA RES INST CHEM TECH (KR)
LEE SANG YUP (KR)
PARK SI JAE (KR)
LEE SEUNG HWAN (KR)
SONG BONG KEUN (KR)
LEE TAE WOO (KR)
KOREA RES INST CHEM TECH (KR)
LEE SANG YUP (KR)
PARK SI JAE (KR)
LEE SEUNG HWAN (KR)
SONG BONG KEUN (KR)
LEE TAE WOO (KR)
International Classes:
C12N1/21; C12N15/52; C12P7/62
Foreign References:
US20080275208A1 | 2008-11-06 | |||
KR20100090019A | 2010-08-13 | |||
KR20090078925A | 2009-07-21 |
Other References:
JIA JIAN ET AL.: "Production ofpolyhydroxyalkanoates by Escherichia coli mutants with defected mixed acid fermentation pathways", APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, vol. 87, no. 6, August 2010 (2010-08-01), pages 2247 - 2256
KEN' ICHIRO MATSUMOTO ET AL.: "Enzymatic and whole-cell synthesis of lactate-containing polyesters: toward the complete biological production of polylactate", APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, vol. 85, no. 4, January 2010 (2010-01-01), pages 921 - 932
YU KYUNG JUNG ET AL.: "Metabolic engineering of Escherichia coli for the production of polylactic acid and its copolymers", BIOTECHNOLOGY AND BIOENGINEERING, vol. 105, no. 1, 1 January 2010 (2010-01-01), pages 161 - 171
TAEK HO YANG ET AL.: "Biosynthesis of polylactic acid and its copolymers using evolved propionate CoA transferase and PHA synthase", BIOTECHNOLOGY AND BIOENGINEERING, vol. 105, no. 1, 1 January 2010 (2010-01-01), pages 150 - 160
YUYANG SONG ET AL.: "Engineered Corynebacterium glutamicum as an endotoxin-free platform strain for lactate-based polyester production", APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, vol. 93, no. 5, 30 November 2011 (2011-11-30), pages 1917 - 1925
KEN' ICHIRO MATSUMOTO ET AL.: "Enzymatic and whole-cell synthesis of lactate-containing polyesters: toward the complete biological production of polylactate", APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, vol. 85, no. 4, January 2010 (2010-01-01), pages 921 - 932
YU KYUNG JUNG ET AL.: "Metabolic engineering of Escherichia coli for the production of polylactic acid and its copolymers", BIOTECHNOLOGY AND BIOENGINEERING, vol. 105, no. 1, 1 January 2010 (2010-01-01), pages 161 - 171
TAEK HO YANG ET AL.: "Biosynthesis of polylactic acid and its copolymers using evolved propionate CoA transferase and PHA synthase", BIOTECHNOLOGY AND BIOENGINEERING, vol. 105, no. 1, 1 January 2010 (2010-01-01), pages 150 - 160
YUYANG SONG ET AL.: "Engineered Corynebacterium glutamicum as an endotoxin-free platform strain for lactate-based polyester production", APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, vol. 93, no. 5, 30 November 2011 (2011-11-30), pages 1917 - 1925
Attorney, Agent or Firm:
LEE, Cheo Young (Yeosam Bldg.648-23, Yeoksam-dong, Gangnam-gu, Seoul 135-080, KR)
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Claims: