Title:
RECOMBINANT POLYNUCLEOTIDE CODING FOR POLYPEPTIDE COMPRISING REPORTER MOIETY, SUBSTRATE MOIETY AND DESTABILIZING MOIETY, HOST CELL COMPRISING SAME AND USE OF SAME
Document Type and Number:
WIPO Patent Application WO/2017/204561
Kind Code:
A3
Abstract:
Provided are recombinant polynucleotide coding for polypeptide comprising a reporter moiety, a substrate moiety and a destabilizing moiety, a host cell comprising same and a method for measuring a protease level by means of same.
Inventors:
JUNG HYUN HO (KR)
YANG GI HYEOK (KR)
LEE JUN HO (KR)
LEE DONG KYU (KR)
LEE YOUNG RAE (KR)
YANG GI HYEOK (KR)
LEE JUN HO (KR)
LEE DONG KYU (KR)
LEE YOUNG RAE (KR)
Application Number:
PCT/KR2017/005420
Publication Date:
January 18, 2018
Filing Date:
May 24, 2017
Export Citation:
Assignee:
MEDYTOX INC (KR)
International Classes:
C12N15/62; C12N5/0793; C12N15/11; C12Q1/37; G01N33/50
Foreign References:
KR20130111954A | 2013-10-11 | |||
KR20150087321A | 2015-07-29 | |||
JP2015509372A | 2015-03-30 |
Other References:
IWAWAKI ET AL.: "Transgenic Mouse Model for Imaging of Interleukin-1beta-related Inflammation in Vivo", SCIENTIFIC REPORTS, vol. 5, 24 November 2015 (2015-11-24), pages 1 - 10, XP055428772
SAINSBURY ET AL.: "Multimodal Protein Constructs for Herbivore Insect Control", TOXINS, vol. 4, 12 June 2012 (2012-06-12), pages 455 - 475, XP055459718
SAINSBURY ET AL.: "Multimodal Protein Constructs for Herbivore Insect Control", TOXINS, vol. 4, 12 June 2012 (2012-06-12), pages 455 - 475, XP055459718
Attorney, Agent or Firm:
Y.P.LEE, MOCK & PARTNERS (KR)
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