Title:
RECOVERY METHOD FOR IMMOBILIZED BIOCATALYSTS
Document Type and Number:
WIPO Patent Application WO2003012196
Kind Code:
A3
Abstract:
Processes for the production of a product by the enzymatic treatment of a soluble of particulate substrate with a particulate, immobilized enzyme, by treating a process liquor containing the substrate in a bioreactor to product a slurry of effluent immobilized enzyme and the product in an effluent liquor. The slurry is subject to a non-immobilized enzyme damaging shear inducing effective separation process to provide effluent immobilized enzyme, and effluent liquor containing the product; and reusing the effluent immobilized enzyme in the enzymatic treatment. The process provides for the reclamation and reuse of the immobilized enzyme even when a further particulate solid is present in the effluent/product stream.
Inventors:
SAVILLE BRADLEY A (CA)
Application Number:
PCT/CA2002/001126
Publication Date:
December 11, 2003
Filing Date:
July 22, 2002
Export Citation:
Assignee:
SAVILLE BRADLEY A (CA)
International Classes:
C12N11/00; C12P19/14; (IPC1-7): C12M1/40; C12P1/00
Domestic Patent References:
| WO1985005561A1 | 1985-12-19 | |||
| WO1992001779A1 | 1992-02-06 | |||
| WO2002055723A1 | 2002-07-18 | |||
| WO1998030710A1 | 1998-07-16 |
Foreign References:
| US4158609A | 1979-06-19 |
Other References:
GANESH K ET AL: "Cellulase deactivation in a stirred reactor", BIOCHEMICAL ENGINEERING JOURNAL, vol. 4, no. 2, 2000, pages 137 - 141, XP002253666, ISSN: 1369-703X
SECCOMBE P: "DEVELOPMENT OF A HYDROCYCLONE BIOREACTOR FOR THE CONTINUOUS CULTURE OF IMMOBILIZED YEAST CELLS", JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY, vol. 51, no. 2, 1991, pages 284 - 285, XP008021484, ISSN: 0268-2575
SECCOMBE P: "DEVELOPMENT OF A HYDROCYCLONE BIOREACTOR FOR THE CONTINUOUS CULTURE OF IMMOBILIZED YEAST CELLS", JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY, vol. 51, no. 2, 1991, pages 284 - 285, XP008021484, ISSN: 0268-2575
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