Title:
REGULATION OF HUMAN FOLLICLE STIMULATING HORMONE-LIKE G PROTEIN-COUPLED RECEPTOR
Document Type and Number:
WIPO Patent Application WO2001088127
Kind Code:
A3
Abstract:
Reagents which regulate human follicle stimulating hormone-like G protein-coupled receptor (FSH-like GPCR) and reagents which bind to human FSH-like GPCR gene products can play a role in preventing, ameliorating, or correcting dysfunctions or diseases including, but not limited to, obesity and diseases related to obesity, cancer, diabetes, osteoporosis, anxiety, depression, hypertension, migraine, compulsive disorders, schizophrenia, autism, neurodegenerative disorders, such as Alzheimer's disease, Parkinsonism, and Huntington's chorea, and cancer chemotherapy-induced vomiting.
Inventors:
RAMAKRISHNAN SHYAM (US)
Application Number:
PCT/EP2001/005613
Publication Date:
September 19, 2002
Filing Date:
May 17, 2001
Export Citation:
Assignee:
BAYER AG (DE)
RAMAKRISHNAN SHYAM (US)
RAMAKRISHNAN SHYAM (US)
International Classes:
C07K14/72; C12N15/12; (IPC1-7): C12N15/12; A61K39/395; A61K48/00; C07K14/72; C12N5/10; C12N15/62; C12Q1/68; G01N33/50; G01N33/53
Domestic Patent References:
| WO2000015793A2 | 2000-03-23 | |||
| WO1993020199A1 | 1993-10-14 | |||
| WO1992016620A1 | 1992-10-01 | |||
| WO2001031014A2 | 2001-05-03 | |||
| WO2001036471A2 | 2001-05-25 | |||
| WO2001068858A2 | 2001-09-20 |
Other References:
DATABASE EMBL SEQUENCE LIBRARY [online] 23 September 1998 (1998-09-23), MAHAIRAS, G.G., ET AL.: "Sequence-tagged connectors: A sequence approach to mapping and scanning the human genome", XP002201373, retrieved from HTTP://SRS6.EBI.AC.UK Database accession no. AQ212353
VANNIER B ET AL: "ANTI-HUMAN FSH RECEPTOR MONOCLONAL ANTIBODIES: IMMUNOCHEMICAL AND IMMUNOCYTOCHEMICAL CHARACTERIZATION OF THE RECEPTOR", BIOCHEMISTRY, AMERICAN CHEMICAL SOCIETY. EASTON, PA, US, vol. 35, no. 5, 1996, pages 1358 - 1366, XP002920191, ISSN: 0006-2960
ALBANESE C ET AL: "DEVELOPMENT OF A BIOASSAY FOR FSH USING A RECOMBINANT HUMAN FSH RECEPTOR AND A CAMP RESPONSIVE LUCIFERASE REPORTER GENE", MOLECULAR AND CELLULAR ENDOCRINOLOGY, AMSTERDAM, NL, vol. 101, February 1994 (1994-02-01), pages 211 - 219, XP000889642, ISSN: 0303-7207
GROMOLL J ET AL: "THE STRUCTURE AND ORGANIZATION OF THE HUMAN FOLLICLE-STIMULATING HORMONE RECEPTOR (FSHR) GENE", GENOMICS, ACADEMIC PRESS, SAN DIEGO, US, vol. 35, 22 March 1996 (1996-03-22), pages 308 - 311, XP001023852, ISSN: 0888-7543
VANNIER B ET AL: "ANTI-HUMAN FSH RECEPTOR MONOCLONAL ANTIBODIES: IMMUNOCHEMICAL AND IMMUNOCYTOCHEMICAL CHARACTERIZATION OF THE RECEPTOR", BIOCHEMISTRY, AMERICAN CHEMICAL SOCIETY. EASTON, PA, US, vol. 35, no. 5, 1996, pages 1358 - 1366, XP002920191, ISSN: 0006-2960
ALBANESE C ET AL: "DEVELOPMENT OF A BIOASSAY FOR FSH USING A RECOMBINANT HUMAN FSH RECEPTOR AND A CAMP RESPONSIVE LUCIFERASE REPORTER GENE", MOLECULAR AND CELLULAR ENDOCRINOLOGY, AMSTERDAM, NL, vol. 101, February 1994 (1994-02-01), pages 211 - 219, XP000889642, ISSN: 0303-7207
GROMOLL J ET AL: "THE STRUCTURE AND ORGANIZATION OF THE HUMAN FOLLICLE-STIMULATING HORMONE RECEPTOR (FSHR) GENE", GENOMICS, ACADEMIC PRESS, SAN DIEGO, US, vol. 35, 22 March 1996 (1996-03-22), pages 308 - 311, XP001023852, ISSN: 0888-7543
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