Title:
REMEDIES FOR CIRRHOSIS
Document Type and Number:
WIPO Patent Application WO/2002/000256
Kind Code:
A1
Abstract:
It is found out that type X sPLA¿2? inhibitors are useful in preventing or treating cirrhosis.
Inventors:
HANASAKI KOHJI (JP)
IKEDA MINORU (JP)
ONO TAKASHI (JP)
IKEDA MINORU (JP)
ONO TAKASHI (JP)
Application Number:
PCT/JP2001/005481
Publication Date:
January 03, 2002
Filing Date:
June 27, 2001
Export Citation:
Assignee:
SHIONOGI & CO (JP)
HANASAKI KOHJI (JP)
IKEDA MINORU (JP)
ONO TAKASHI (JP)
HANASAKI KOHJI (JP)
IKEDA MINORU (JP)
ONO TAKASHI (JP)
International Classes:
A61K31/403; A61K31/404; A61K31/405; A61K31/437; A61K31/4985; A61K31/5025; A61P1/16; C07D209/32; C07D209/88; C07D403/04; C07D487/04; (IPC1-7): A61K45/00; A61K31/4985; A61K31/437; A61K31/5025; A61K31/403; A61K31/404; A61P1/16
Domestic Patent References:
| WO2001026653A1 | 2001-04-19 |
Foreign References:
| EP0952149A2 | 1999-10-27 | |||
| EP0675110A1 | 1995-10-04 |
Other References:
MURAKAMI M. ET AL.: "Different functional aspects of the group II subfamily (types IIA and V) and type X secretory phospholipase A(2)s in regulating arachidonic acid release and prostaglandin generation. Implications of cyclooxygenase-2 induction and phospholipid scramblase-mediated cellular membrane perturbation", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 274, no. 44, 29 October 1999 (1999-10-29), pages 31435 - 31444, XP002945999
Attorney, Agent or Firm:
Yamauchi, Hideaki (Ltd. Intellectual Property Department 12-4
Sagisu 5-chom, Fukushima-ku Osaka-shi Osaka, JP)
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