REMEDIES FOR LUNG CANCER

WIPO Patent Application WO/2002/060453

A1

Lung cancer can be efficaciously treated by the combined use of amrubicin or its pharmaceutically acceptable salt with cisplatin.

NOGUCHI TOSHIHIRO (JP)
BABA AKEMI (JP)

PCT/JP2002/000672

August 08, 2002

January 29, 2002

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SUMITOMO PHARMA (JP)
NOGUCHI TOSHIHIRO (JP)
BABA AKEMI (JP)

A61K31/65; A61K33/243; A61K45/06; A61P11/00; A61P35/00; (IPC1-7): A61K31/704; A61K33/24; A61P35/00; A61P11/00; C07H15/252

TATSUYA TAKAGI ET AL.: "Effects of 13-hydroxy SM5887 in combination with other anticancer agents on human cell lines", INVESTIGATIONAL NEW DRUGS, vol. 14, 1996, pages 357 - 363, XP002951001
TOYOAKI HIDA ET AL.: "Cyclooxygenase-2 inhibitor induces apoptosis and enhances cytotoxicity of various anticancer agents in non-small cell lung cancer cell lines", CLINICAL CANCER RESEARCH, vol. 6, 2000, pages 2006 - 2011, XP002951002
YUICHIRO OHE ET AL.: "In vitro evaluation of the new anticancer agents KT6149, MX-2, SM5887, menogariland liblomycin using cisplatin- or adriamycin-resistant human cancer cell lines", CANCER RESEARCH, vol. 49, 1989, pages 4098 - 4102, XP000900552
J. ORG. CHEM., vol. 52, 1987, pages 4477 - 4485
See also references of EP 1364652A4

Isobe, Yutaka c/o Intellectual Property Department SUMITOMO PHARMACEUTICALS CO. (LTD. 1-98 Kasugadenaka 3-chom, Konohana-ku Osaka-shi Osaka, JP)

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