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Title:
Aβ-REMOVER, Aβ-REMOVING APPARATUS, AND Aβ REMOVAL METHOD
Document Type and Number:
WIPO Patent Application WO/2010/073580
Kind Code:
A1
Abstract:
Disclosed are a material capable of removing Aβ from a body fluid efficiently and use of the material, which are developed for the purpose of establishing a therapeutic or prophylactic method for Alzheimer's disease. Specifically disclosed is an amyloid-β protein remover which comprises a carrier made of a material selected from the group consisting of cellulose, silica, polyvinyl alcohol and activated carbon and having no alkyl chain or having a C1-18 alkyl chain on the surface thereof.

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Inventors:
KITAGUCHI NOBUYA (JP)
KAWAGUCHI KAZUNORI (JP)
Application Number:
PCT/JP2009/007051
Publication Date:
July 01, 2010
Filing Date:
December 21, 2009
Export Citation:
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Assignee:
UNIV FUJITA HEALTH (JP)
KANEKA CORP (JP)
KITAGUCHI NOBUYA (JP)
KAWAGUCHI KAZUNORI (JP)
International Classes:
A61M1/36; A61K35/14; A61M1/02; A61M1/16; A61P25/28
Foreign References:
JP2007504863A2007-03-08
JPH01135533A1989-05-29
JP2008069346A2008-03-27
JP2005537254A2005-12-08
JP2008050665A2008-03-06
Other References:
BAYER A ET AL., NEUROLOGY, vol. 64, 2005, pages 94 - 101
HOLMES C ET AL., LANCET., vol. 372, no. 9634, 19 July 2008 (2008-07-19), pages 216 - 23
LEMERE, C. A. ET AL., NUEROBIOL. DIS., vol. 14, 2003, pages 10 - 18
MATSUOKA Y. ET AL., J. NEUROSCI., vol. 23, 2003, pages 29 - 33
BERGAMASCHINI, L. ET AL., J. NEUROSCI., vol. 24, 2004, pages 4148 - 4186
LEVITES, Y. ET AL., J. NEUROSCI., vol. 26, 2006, pages 11923 - 11928
KYOTO MEDICAL JOURNAL, vol. 53, no. 1, June 2006 (2006-06-01), pages 113 - 120
ISABEL RUBIO ET AL., JOURNAL OF ALZHEIMER'S DISEASE, vol. 10, 2006, pages 439 - 443
TAKASHI AKIBA, MICHIO MINESHIMA: "Hemocatharsis Therapy", NANKODO CO., LTD., pages: 228
Attorney, Agent or Firm:
HAGINO, Mikiharu (JP)
Kanji Hagino (JP)
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