Title:
REPLICABILITY VIRUS WHICH CAN EXPRESS ANTI-TUMOUR ANTIBODY WITH HIGH EFFICIENCY AND THE USE OF IT
Document Type and Number:
WIPO Patent Application WO/2004/007703
Kind Code:
A1
Abstract:
The invention provided a replicability virus which can express anti-tumour antibody or its segment with high efficiency and the use of it. The propagate of this virus was only in tumour cell. The nucleotide sequence which code anti-tumour antibody or its segment was inserted into the replicability virus genome, and the copies of this nucleotide sequence increased with the propagate of this replicability virus in tumour cell, so the virus can express anti-tumour antibody or its segment with high efficiency in tunour cell and restrained the upgrowth and tranfer of tumours.
Inventors:
QIAN QIJUN (CN)
YANG QIN (CN)
YANG QIN (CN)
Application Number:
PCT/CN2003/000565
Publication Date:
January 22, 2004
Filing Date:
July 15, 2003
Export Citation:
Assignee:
SINO GENE BIOTECHNOLOGY LTD (CN)
QIAN QIJUN (CN)
YANG QIN (CN)
QIAN QIJUN (CN)
YANG QIN (CN)
International Classes:
A61K35/76; A61P35/00; C07K16/30; C12N7/01; C12N15/13; C12N15/33; A61K39/00; (IPC1-7): C12N7/01; A61K39/395; A61P35/00; C07K16/00; C12N15/09; C12N15/13; C12N15/33; C12N15/861
Domestic Patent References:
| WO2001007481A1 | 2001-02-01 | |||
| WO1995018866A1 | 1995-07-13 |
Attorney, Agent or Firm:
CCPIT PATENT AND TRADEMARK LAW OFFICE (Vantone New World Plaza 2 Fuchengmenwai Street, Beijing 7, CN)
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