Title:
RESORCINOL DIANISOLE DERIVATIVE AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2020/173016
Kind Code:
A1
Abstract:
The present invention relates to a resorcinol dianisole derivative, wherein the chemical structure of this compound is as represented by the following formula (I). The compound of the present invention can inhibit the binding of programmed cell death receptor 1/programmed cell death ligand 1 (PD-1/PD-L1), and can be used for preparing a PD-1/PD-L1 inhibitor. The inhibitor has a significant anti-tumor effect.
Inventors:
CHEN JIANJUN (CN)
CHENG BINBIN (CN)
CHENG BINBIN (CN)
Application Number:
PCT/CN2019/091193
Publication Date:
September 03, 2020
Filing Date:
June 14, 2019
Export Citation:
Assignee:
UNIV SOUTHERN MEDICAL (CN)
International Classes:
C07C255/54; A61K31/277; A61P35/00; C07D205/04; C07D207/12; C07D207/16; C07D319/18; C07D405/12
Foreign References:
| CN109761952A | 2019-05-17 | |||
| CN109503546A | 2019-03-22 | |||
| CN106536515A | 2017-03-22 | |||
| CN109305934A | 2019-02-05 | |||
| CN109219592A | 2019-01-15 |
Attorney, Agent or Firm:
GUANGZHOU TIANHE LUYANG PATENT OFFICE (GENERAL PARTNERSHIP) (CN)
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