Title:
RETINOID-ASSOCIATED RECEPTOR REGULATORS
Document Type and Number:
WIPO Patent Application WO/2000/001679
Kind Code:
A1
Abstract:
Retinoid-associated receptor regulators containing 1,3-azole derivatives represented by general formula (I) or salts thereof wherein R?1¿ represents optionally substituted aromatic hydrocarbyl or heteroaryl; R?2¿ represents hydrogen or optionally substituted hydrocarbyl; X represents O, s or -NR?4¿-; A represents optionally substituted aromatic hydrocarbyl or heteroaryl; and R?3¿ represents -OR?5¿ or -NR?6¿R?7¿. These products are usable as, for example, preventives and remedies for diabetes, etc.
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Inventors:
SUGIYAMA YASUO (JP)
MOMOSE YU (JP)
KIMURA HIROYUKI (JP)
SAKAMOTO JUNICHI (JP)
ODAKA HIROYUKI (JP)
MOMOSE YU (JP)
KIMURA HIROYUKI (JP)
SAKAMOTO JUNICHI (JP)
ODAKA HIROYUKI (JP)
Application Number:
PCT/JP1999/003520
Publication Date:
January 13, 2000
Filing Date:
June 30, 1999
Export Citation:
Assignee:
TAKEDA CHEMICAL INDUSTRIES LTD (JP)
SUGIYAMA YASUO (JP)
MOMOSE YU (JP)
KIMURA HIROYUKI (JP)
SAKAMOTO JUNICHI (JP)
ODAKA HIROYUKI (JP)
SUGIYAMA YASUO (JP)
MOMOSE YU (JP)
KIMURA HIROYUKI (JP)
SAKAMOTO JUNICHI (JP)
ODAKA HIROYUKI (JP)
International Classes:
C07D233/54; C07D263/32; C07D277/30; C07D413/04; C07D417/04; (IPC1-7): C07D263/30; C07D277/30; C07D413/04; C07D417/04; A61K31/42; A61K31/425; A61K31/44
Domestic Patent References:
| WO1998052967A1 | 1998-11-26 | |||
| WO1996026206A1 | 1996-08-29 | |||
| WO1998008830A1 | 1998-03-05 |
Foreign References:
| JPS5163844A | 1976-06-02 | |||
| JPH02240058A | 1990-09-25 | |||
| JPH01156736A | 1989-06-20 | |||
| JPH072851A | 1995-01-06 | |||
| JPH10101562A | 1998-04-21 | |||
| JPH04154773A | 1992-05-27 | |||
| JPS47784A | 1972-01-14 | |||
| JPH10152437A | 1998-06-09 | |||
| JPH0665222A | 1994-03-08 | |||
| US4001420A | 1977-01-04 | |||
| JPH04128274A | 1992-04-28 | |||
| JPS62178590A | 1987-08-05 | |||
| JPH1059951A | 1998-03-03 |
Other References:
V. TKACHEV ET AL.,, MOL. MATS., vol. 1, no. 2, 1992, pages 169 - 174, XP002927036
KEVEN BROWN ET AL.,, JOURNAL OF MEDICAL CHEMISTRY, vol. 17, no. 11, 1974, pages 1177 - 1181, XP002927038
MASATOSHI CHIHIRO ET AL.,, J. MED. CHEM, vol. 38, no. 2, 1995, pages 353 - 358, XP002927037
See also references of EP 1092711A4
KEVEN BROWN ET AL.,, JOURNAL OF MEDICAL CHEMISTRY, vol. 17, no. 11, 1974, pages 1177 - 1181, XP002927038
MASATOSHI CHIHIRO ET AL.,, J. MED. CHEM, vol. 38, no. 2, 1995, pages 353 - 358, XP002927037
See also references of EP 1092711A4
Attorney, Agent or Firm:
Asahina, Tadao (Ltd. 17-85, Jusohonmachi 2-chome Yodogawa-ku Osaka-shi Osaka, JP)
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