RHO-ASSOCIATED PROTEIN KINASE INHIBITOR, PHARMACEUTICAL COMPOSITION CONTAINING RHO-ASSOCIATED PROTEIN KINASE INHIBITOR, PREPARATION METHOD AND USE OF THE PHARMACEUTICAL COMPOSITION

Title:

RHO-ASSOCIATED PROTEIN KINASE INHIBITOR, PHARMACEUTICAL COMPOSITION CONTAINING RHO-ASSOCIATED PROTEIN KINASE INHIBITOR, PREPARATION METHOD AND USE OF THE PHARMACEUTICAL COMPOSITION

Document Type and Number:

WIPO Patent Application WO/2019/000683

Kind Code:

A1

Abstract:

Provided are a Rho-associated protein kinase (ROCK) inhibitor of formula (I), a pharmaceutical composition containing said Rho-associated protein kinase inhibitor, a preparation method thereof and an application of the ROCK for treating and preventing rock-mediated disease.

Inventors:

ZHAO YANPING (CN)
WANG HONGJUN (CN)
LI GONG (CN)
JIANG YUANYUAN (CN)
LI XIANG (CN)
ZHOU LIYING (CN)
LIU YANAN (CN)

Application Number:

PCT/CN2017/104294

Publication Date:

January 03, 2019

Filing Date:

September 29, 2017

Export Citation:

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Assignee:

BEIJING TIDE PHARMACEUTICAL CO LTD (CN)

International Classes:

C07D403/14; A61K31/506; A61P35/00; A61P37/00; C07D405/14; C07D409/14; C07D413/14; C07D417/14; C07D471/04; C07D487/04; C07D495/04

Domestic Patent References:

WO2017048675A1

2017-03-23

Foreign References:

CN106478651A	2017-03-08
CN104903320A	2015-09-09
CN104334553A	2015-02-04
CN101228161A	2008-07-23

Attorney, Agent or Firm:

NTD UNIVATION INTELLECTUAL PROPERTY AGENCY LTD. (CN)

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