RIBOFURANOSYL PYRIDINE DERIVATIVE, AND PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF

WIPO Patent Application WO/2023/104039

A1

The present invention relates to the field of medicines, and specifically relates to a ribofuranosyl pyridine derivative, and a pharmaceutical composition thereof and a use thereof. The present invention provides a compound as shown in formula I below, and a racemate, stereoisomer, tautomer, isotopic label, solvate or prodrug thereof, which have very excellent anti-tumor activity and have important significance for treating tumor diseases.

JP2007527396	Synthesis of β-L-2'-deoxynucleoside
WO/2021/214299	NICOTINAMIDE MONONUCLEOTIDE AND NICOTINAMIDE RIBOSIDE DERIVATIVES AND USE THEREOF IN THE TREATMENT OF VIRAL INFECTIONS AND RESPIRATORY COMPLICATIONS, IN PARTICULAR CAUSED BY INFLUENZAVIRUS OR CORONAVIRUS
WO/2017/145151	PROCESS FOR PREPARATION OF NICOTINAMIDE RIBOSIDE (NR) AND COSMETIC COMPOSITION COMPRISING (NR AND A PHOSPHATE-BINDING AGENT

ZHU XINFA (CN)
ZHU RAN (CN)

PCT/CN2022/136963

June 15, 2023

December 06, 2022

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NINGBO XIJIAN PHARMACEUTICAL TECH CO LTD (CN)

C07H19/048; A61K31/706; A61P35/00; C07H1/00

WO2020191359A1	2020-09-24
WO2021013795A2	2021-01-28

CN115232184A	2022-10-25
CN115400140A	2022-11-29
CN106715455A	2017-05-24
CN111909229A	2020-11-10
CN107531738A	2018-01-02
CN113727987A	2021-11-30

MAKAROV, M. V. ET AL.: "Scalable Syntheses of Traceable Ribosylated NAD+ Precursors", ORG. BIOMOL. CHEM., 13 September 2019 (2019-09-13), XP055812690
DATABASE Registry 18 February 2021 (2021-02-18), ANONYMOUS : "INDEX NAME NOT YET ASSIGNED ", XP093071503, retrieved from STN Database accession no. 2591503-94-3

BEIJING ORIGINTELLIGENCE IP LAW FIRM (CN)

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