Title:
RINGLIKE FLAVONE OR ISOFLAVONE COMPOUND, AND APPLICATION OF SAME
Document Type and Number:
WIPO Patent Application WO/2015/067108
Kind Code:
A1
Abstract:
Disclosed is ringlike flavone shown by the formula (I), or an isoflavone compound, or nitric oxide, hydrate, solvate, or metabolite thereof, or pharmaceutically accepted salt or prodrug. A2 is -O- when A is -C(O)-; A2 is -C(O)- when A is -O-; Q is -O-、-S-、-C(R4R5)-、-C(R4R5)O-、-OC(R4R5)-、-C(R4R5)N(R6)-、-N(R6)C(R4R5)-、-N(R6)-、-C(R4R5)C(R4R5)-、-C(R4R5)-S- or -S-C(R4R5)-; W is -(NHC(O))1~2-、-(C1-C3) alkylene-(NHC(O))1~2-, formula (II), formula (III),formula (IV), or formula (V); or R1 is connected to W to form the imidazole ring. The ringlike flavone or isoflavone compound of the present invention has a desirable anti-hepatitis C virus effect.
Inventors:
ZHANG SUOMING (CN)
Application Number:
PCT/CN2014/087879
Publication Date:
May 14, 2015
Filing Date:
September 30, 2014
Export Citation:
Assignee:
SHANGHAI TANGRUN PHARMACEUTICALS CO LTD (CN)
International Classes:
C07D493/04; A61K31/33; A61P1/16; A61P31/14; C07D519/00
Domestic Patent References:
| WO2012130893A1 | 2012-10-04 |
Foreign References:
| CN101744830A | 2010-06-23 | |||
| CN101822372A | 2010-09-08 | |||
| CN101301287A | 2008-11-12 | |||
| CN102379888A | 2012-03-21 | |||
| CN101955478A | 2011-01-26 | |||
| CN102247395A | 2011-11-23 |
Attorney, Agent or Firm:
WEI YUAN PATENT LAW L.L.C (CN)
上海唯源专利代理有限公司 (CN)
上海唯源专利代理有限公司 (CN)
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