Title:
RNA MICRO-ARRAY FOR DETECTING INTERACTION BETWEEN PROTEIN AND CONFORMATION-CONTAINING RNA
Document Type and Number:
WIPO Patent Application WO/2015/105179
Kind Code:
A1
Abstract:
Interaction with protein is detected using an RNA probe containing the following sequences: (i) complementary strand to DNA bar-code sequence; (ii) sequence of first stem portion; (iii) the sequence of a second stem portion that is complementary to the first step portion, to hybridize with the first stem part and form a double-strand stem; and (iv) the sequence of a loop portion contained in RNA that concatenates the first and second stem portions.
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Inventors:
SAITO HIROHIDE (JP)
TAYA TOSHIKI (JP)
KASHIDA SHUNICHI (JP)
TAYA TOSHIKI (JP)
KASHIDA SHUNICHI (JP)
Application Number:
PCT/JP2015/050494
Publication Date:
July 16, 2015
Filing Date:
January 09, 2015
Export Citation:
Assignee:
UNIV KYOTO (JP)
International Classes:
C12N15/09; C12M1/00; C12N15/11; C12Q1/68; G01N37/00
Domestic Patent References:
WO2009066758A1 | 2009-05-28 | |||
WO2010067811A1 | 2010-06-17 |
Foreign References:
JP2007529994A | 2007-11-01 | |||
JP2006520206A | 2006-09-07 | |||
US20110230367A1 | 2011-09-22 | |||
JP2009142273A | 2009-07-02 | |||
JPH10507357A | 1998-07-21 | |||
JP2002518060A | 2002-06-25 | |||
JP2001519648A | 2001-10-23 | |||
JP2002181813A | 2002-06-26 |
Other References:
KEENE, J.D.: "Nature reviews", GENETICS, vol. 8, 2007, pages 533 - 543
NAM, Y.; CHEN, C.; GREGORY, R.I. ET AL., CELL, vol. 147, 2011, pages 1080 - 1091
RAY, D.; KAZAN, H.; COOK, K.B. ET AL., NATURE, vol. 499, 2013, pages 172 - 177
XU, Q.; SCHLABACH, M.R.; HANNON, G.J. ET AL., PNAS, vol. 106, 2009, pages 2289 - 2294
SAITO H; FUJITA Y; KASHIDA S ET AL., NAT. COMMUN, vol. 2, 2011, pages 160
KASHIDA S; INOUE T; SAITO H., NUCLEIC ACIDS RES., vol. 40, 2012, pages 9369 - 78
See also references of EP 3093342A4
NAM, Y.; CHEN, C.; GREGORY, R.I. ET AL., CELL, vol. 147, 2011, pages 1080 - 1091
RAY, D.; KAZAN, H.; COOK, K.B. ET AL., NATURE, vol. 499, 2013, pages 172 - 177
XU, Q.; SCHLABACH, M.R.; HANNON, G.J. ET AL., PNAS, vol. 106, 2009, pages 2289 - 2294
SAITO H; FUJITA Y; KASHIDA S ET AL., NAT. COMMUN, vol. 2, 2011, pages 160
KASHIDA S; INOUE T; SAITO H., NUCLEIC ACIDS RES., vol. 40, 2012, pages 9369 - 78
See also references of EP 3093342A4
Attorney, Agent or Firm:
OKUYAMA, Shoichi et al. (JP)
Okuyama In addition, it is 1. (JP)
Okuyama In addition, it is 1. (JP)
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