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Patent Searching and Data


Title:
ROPINIROLE-CONTAINING ADHESIVE PATCH
Document Type and Number:
WIPO Patent Application WO/2014/084311
Kind Code:
A1
Abstract:
The purpose of the present invention is to provide an adhesive patch that is obtained by blending ropinirole, which is in a free form, in an adhesive base, said adhesive patch having good and lasting percutaneous absorption, excellent medicinal ingredient stability and excellent adhesiveness. Provided is a transdermal adhesive patch that is obtained by blending ropinirole, which is in a free form, in an adhesive base that is obtained by compounding a styrene-isoprene-styrene block copolymer (SIS), a softening agent and one or more kinds of tackifying resins each containing a rosin resin. This transdermal adhesive patch is characterized in that the blending ratio of the rosin resin to the ropinirole in a free form, namely (the blending weight of the rosin resin)/(the ropinirole in a free form) is 3.5-8.0. In particular, a ropinirole-containing adhesive patch wherein the rosin resin is a hydrogenated rosin glycerol ester and the softening agent is a liquid paraffin.

Inventors:
INOO KATSUYUKI (JP)
KATAYAMA AKIKO (JP)
TAKANO DAIKI (JP)
Application Number:
PCT/JP2013/082055
Publication Date:
June 05, 2014
Filing Date:
November 28, 2013
Export Citation:
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Assignee:
TEIKOKU SEIYAKU KK (JP)
International Classes:
A61K31/4045; A61K9/70; A61K47/06; A61K47/14; A61K47/32; A61P25/16
Domestic Patent References:
WO2009107478A12009-09-03
WO2010134433A12010-11-25
WO2012165254A12012-12-06
WO2012165253A12012-12-06
WO2013081102A12013-06-06
WO2009107478A12009-09-03
Foreign References:
JP2010280634A2010-12-16
JP2001518058A2001-10-09
JPH11506462A1999-06-08
Other References:
See also references of EP 2926814A4
Attorney, Agent or Firm:
KUSAMA, OSAMU (JP)
Osamu Kusama (JP)
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