Title:
ROTATING NANOWIRE AND METHOD FOR INDUCING CELL NECROSIS USING SAME
Document Type and Number:
WIPO Patent Application WO/2012/105796
Kind Code:
A3
Abstract:
The present invention provides a cell necrosis method and a cell necrosis principle for necrotizing a cell by agitating a cell using a physical turning force from the impression of an exchange magnetic field, after preparing a magnetic nanowire having a dipole and introducing the magnetic nanowire into a cell. Therefore, the composition for inducing a cell necrosis of the present invention, when applied to a cell that is requested to be removed along with a cancer cell, can necrotize the cell by applying a physical shock through the rotation of the nanowire introduced inside the cell. Additionally, the heat generated from induced current from the magnetic field impression can add an effect of thermotherapy, and also, attaching a drug to the surface of the nanowire enhances the treatment effects.
Inventors:
CHOI SUNG HOI (US)
PARK JUNG RAE (US)
KIM YOUNG KEUN (KR)
PARK JUNG RAE (US)
KIM YOUNG KEUN (KR)
Application Number:
PCT/KR2012/000742
Publication Date:
November 29, 2012
Filing Date:
January 31, 2012
Export Citation:
Assignee:
UNIV KOREA RES & BUS FOUND (KR)
CHOI SUNG HOI (US)
PARK JUNG RAE (US)
KIM YOUNG KEUN (KR)
CHOI SUNG HOI (US)
PARK JUNG RAE (US)
KIM YOUNG KEUN (KR)
International Classes:
A61N2/00; A61B18/04; A61L31/02; A61N1/32; A61N2/02
Foreign References:
| US20020187504A1 | 2002-12-12 | |||
| US20080014442A1 | 2008-01-17 | |||
| KR20080074423A | 2008-08-13 |
Other References:
FAN, DONGLEI ET AL.: "Subcellular-resolution delivery of a cytokine through precisely manipulated nanowires.", NATURE NANOTECHNOLOGY, vol. 5, no. 7, July 2010 (2010-07-01), pages 545 - 551, XP055127909
See also references of EP 2671613A4
See also references of EP 2671613A4
Attorney, Agent or Firm:
DANA PATENT LAW FIRM (BYCbldg. Teheran-ro7-gil,Gangnam-gu, Seoul 135-080, KR)
Download PDF:
Claims: