Title:
S-(-)-1-PROPYL-2',6'-AMINOXYLENEFORMYLPIPERIDINE CRYSTAL AND SUSTAINED RELEASE PREPARATION THEREOF
Document Type and Number:
WIPO Patent Application WO/2017/036408
Kind Code:
A1
Abstract:
Provided are a long-effective amide local anesthetic: S-(-)-1-propyl-2',6'-aminoxyleneformylpiperidine crystal, a sustained release preparation thereof, and their preparation method. Compared with an existing hydrochloride preparation, the preparation made from the crystal has a particularly good property of continuously and slowly releasing drug and maintaining an effective blood drug concentration, and shows an excellent long-term local analgesic effect.
Inventors:
YE QIANG (CN)
YAN PANGKE (CN)
FENG WEI (CN)
WAN HUA (CN)
ZHANG XUANMIAO (CN)
WANG DONGHAI (CN)
YAN PANGKE (CN)
FENG WEI (CN)
WAN HUA (CN)
ZHANG XUANMIAO (CN)
WANG DONGHAI (CN)
Application Number:
PCT/CN2016/097784
Publication Date:
March 09, 2017
Filing Date:
September 01, 2016
Export Citation:
Assignee:
SICHUAN HAISCO PHARMACEUTICAL CO LTD (CN)
International Classes:
C07D211/60; A61K9/10; A61K9/19; A61K9/22; A61P23/02
Domestic Patent References:
| WO2009089841A1 | 2009-07-23 |
Foreign References:
| CN104146972A | 2014-11-19 | |||
| CN103142458A | 2013-06-12 | |||
| US20060276654A1 | 2006-12-07 | |||
| US4695576A | 1987-09-22 | |||
| CN103086954A | 2013-05-08 |
Attorney, Agent or Firm:
BEIJING SANYOU INTELLECTUAL PROPERTY AGENCY LTD. (CN)
Download PDF: