Title:
SALICYLIC ACID TRANS-(Β)-FARNESENE ANALOGUES AND USES THEREOF
Document Type and Number:
WIPO Patent Application WO/2016/127723
Kind Code:
A1
Abstract:
The present invention relates to the field of organic compound synthesis. Disclosed are salicylic acid trans-(β)-farnesene analogues, and a preparation method therefor and uses thereof. The compound is obtained by: mixing salicylic acid and analogues thereof, geraniol, geranylamine or substituted geranylamine serving as raw materials with an organic solvent, carrying out a condensation reaction to obtain the salicylic acid trans-(β)-farnesene analogues with different substitutes, and carrying out silica-gel column chromatography separation and purification, so as to obtain the compound represented by formula I. The compound preparation method has mild reaction, simple and easy operations, a high yield and low cost; and the compound is more stable than trans-(β)-farnesene. The compound represented by the formula I has multiple biological activities, a good killing activity to aphids at a high dose, a warning repellant activity to aphids at a low dose, a tobacco mosaic virus resisting activity and a bactericidal activity, can be used for pest control and disease prevention in the agricultural production, and has high application and development value.
Inventors:
YANG XINLING (CN)
QIN YAOGUO (CN)
SONG DUNLUN (CN)
ZHANG JINGPENG (CN)
LING YUN (CN)
TAN XIAOQING (CN)
QU YANYAN (CN)
LI WENHAO (CN)
QIN YAOGUO (CN)
SONG DUNLUN (CN)
ZHANG JINGPENG (CN)
LING YUN (CN)
TAN XIAOQING (CN)
QU YANYAN (CN)
LI WENHAO (CN)
Application Number:
PCT/CN2016/000006
Publication Date:
August 18, 2016
Filing Date:
January 05, 2016
Export Citation:
Assignee:
UNIV CHINA AGRICULTURAL (CN)
International Classes:
C07C69/92; C07C67/03; C07C67/08; C07C69/84; C07C201/12; C07C205/60; C07C231/02; C07C235/60; A01P1/00; A01P3/00; A01P7/04
Domestic Patent References:
| WO2013157926A1 | 2013-10-24 |
Foreign References:
| CN104693035A | 2015-06-10 | |||
| US6333432B1 | 2001-12-25 |
Other References:
GARCIA SANTOS, WILLIAM H. ET AL.: "Gd(OTf)3-Catalyzed Synthesis of Geranyl Esters for the Intramolecular Radical Cyclization of their Epoxides Mediated by Titanocene (III", ORGANIC & BIOMOLECULAR CHEMISTRY, vol. 13, no. 5, 18 November 2014 (2014-11-18), pages 1358 - 1366, ISSN: 1477-0520
Attorney, Agent or Firm:
BEIJING ZHCC INTELLECTUAL PROPERTY CO., LTD (CN)
北京众合诚成知识产权代理有限公司 (CN)
北京众合诚成知识产权代理有限公司 (CN)
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