Title:
SALIVA GLUCOSE MONITORING SYSTEM
Document Type and Number:
WIPO Patent Application WO/2014/110492
Kind Code:
A3
Abstract:
A glucose sensor suitable for measuring glucose levels in human saliva is provided. Systems containing the glucose sensor and methods for making and using the sensor are also provided. The glucose sensor is highly sensitive and can detect glucose levels at least down to 5 ppm. Fabrication of the sensor involves depositing single-walled carbon nanotubes onto the surface of a working electrode in a 3 electrode electrochemical detector and functionalizing the nanotubes by depositing layers of polymers, metallic nanoparticles, and glucose oxidase enzyme onto the nanotubes. The sensor can be used as a disposable, single-use device or as part of an analytical system, such as a microfluidics system, for the analysis of multiple analytes. The sensor enables the diagnosis and monitoring of diabetes to be performed without pain or the need for finger pricks in a home or clinical setting.
Inventors:
ZHANG WENJUN (US)
WANG MING L (US)
WANG MING L (US)
Application Number:
PCT/US2014/011262
Publication Date:
November 26, 2015
Filing Date:
January 13, 2014
Export Citation:
Assignee:
UNIV NORTHEASTERN (US)
International Classes:
A61B5/00; A61B5/145; A61B5/1486; C12Q1/00; C12Q1/54; C25D7/00; G01N27/333; G01N33/50
Domestic Patent References:
| WO2012075331A2 | 2012-06-07 |
Foreign References:
| US20090045055A1 | 2009-02-19 | |||
| US20080029390A1 | 2008-02-07 |
Other References:
See also references of EP 2943784A4
Attorney, Agent or Firm:
HYMEL, Lin, J. (Graf Raulerson & Middleton, PA,300 TradeCenter, Suite 700, Woburn MA, US)
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