Title:
SALT OF ANTITUMOR DRUG AND CRYSTAL FORM THEREOF
Document Type and Number:
WIPO Patent Application WO/2023/061437
Kind Code:
A1
Abstract:
The present invention relates to a salt of an antitumor drug and a crystal form thereof, and specifically relates to a pharmaceutical salt of the compound N-(3-(2-((2-methoxy-4-(4-methyl-1-piperazinyl)phenyl)amino)-7-oxo-6-phenyl-8(7H)-pteridyl)phenyl)acrylamide, and a crystal thereof. The pharmaceutical salt and the crystal thereof in the present invention have excellent solubility and stability, and can be used for treating related diseases mediated by EGFR.
Inventors:
LI WENHUA (CN)
TIAN SONGCHUAN (CN)
ZHU MINGHUI (CN)
TIAN SONGCHUAN (CN)
ZHU MINGHUI (CN)
Application Number:
PCT/CN2022/125069
Publication Date:
April 20, 2023
Filing Date:
October 13, 2022
Export Citation:
Assignee:
SHANGHAI HUILUN PHARMACEUTICAL CO LTD (CN)
International Classes:
C07D475/00; A61K31/519; A61P35/00; C07C55/10; C07C57/145; C07C57/15; C07C59/245; C07C59/255; C07C59/265; C07C233/83; C07C309/04; C07C309/29
Domestic Patent References:
| WO2022042755A1 | 2022-03-03 |
Foreign References:
| CN106279173A | 2017-01-04 | |||
| CN108721298A | 2018-11-02 |
Attorney, Agent or Firm:
HFG INTELLECTUAL PROPERTY AGENCY CO., LTD (CN)
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