Title:
SALT OF DITHIOCARBAMIC ACID, PRODUCTION THEREOF, AND PRODUCTION OF ISOTHIOCYANATE FROM SAID SALT
Document Type and Number:
WIPO Patent Application WO/1992/013835
Kind Code:
A1
Abstract:
Salts of dithiocarbamic acid which can be converted into isothiocyanates, which are suitable intermediates for producing thiazabicyclononane derivatives and monothiourazole derivatives, in a remarkably high yield; a process for producing the salts in a high yield without the necessity for using thiophosgene which is problematic in toxicity; and a process for producing isothiocyanates from the salts. The salt is a compound represented by general formula (2) and produced by the reaction of an aniline represented by general formula (5) with carbon disulfide in the presence of 1,4-diazabicyclo[2.2.2]octane (3) or 4-pyrrolidinopyridine (4). The isothiocyanate (1) is produced by the reaction of the salt (2) with a halogen compound.
Inventors:
YAMAGUCHI MIKIO (JP)
OHI HIDEO (JP)
OHI HIDEO (JP)
Application Number:
PCT/JP1992/000082
Publication Date:
August 20, 1992
Filing Date:
January 29, 1992
Export Citation:
Assignee:
IHARA CHEMICAL IND CO (JP)
International Classes:
C07C331/28; C07C333/16; C07D213/74; C07D487/08; (IPC1-7): C07C331/28; C07C333/16; C07D401/04; C07D487/08
Foreign References:
| JPS6333358A | 1988-02-13 | |||
| JPH02193961A | 1990-07-31 | |||
| JPH02188588A | 1990-07-24 | |||
| JPH01250388A | 1989-10-05 |
Other References:
See also references of EP 0523244A4
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