SALT FORM OF A CONJUGATE USEFUL IN THE TREATMENT OF PROSTATE CANCER

Title:

SALT FORM OF A CONJUGATE USEFUL IN THE TREATMENT OF PROSTATE CANCER

Document Type and Number:

WIPO Patent Application WO2001030804

Kind Code:

A3

Abstract:

The present invention is directed to the sodium salt of formula (5) which may be useful in the treatment of prostate cancer and benign prostatic hyperplasia. Also described are lyophilized formulations that comprise the sodium salt 5 or the corresponding free acid.

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Inventors:

KARKI SHYAM B (US)
CAMERON MARK (US)
LIEBERMAN DAVID R (US)
LYNCH JOSEPH E (US)
ROBBINS MICHAEL A (US)
SHI YAO-JUN (US)
ALMARSSON ORN (US)
KAUFMAN MICHAEL J (US)
NERURKAR MANEESH J (US)

Application Number:

PCT/US2000/029610

Publication Date:

January 10, 2002

Filing Date:

October 27, 2000

Export Citation:

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Assignee:

MERCK & CO INC (US)
KARKI SHYAM B (US)
CAMERON MARK (US)
LIEBERMAN DAVID R (US)
LYNCH JOSEPH E (US)
ROBBINS MICHAEL A (US)
SHI YAO JUN (US)
ALMARSSON ORN (US)
KAUFMAN MICHAEL J (US)
NERURKAR MANEESH J (US)

International Classes:

A61K9/19; A61K38/00; A61K47/12; A61K47/26; A61K47/48; A61P13/08; A61P35/00; C07K1/30; C07K9/00; (IPC1-7): C07K14/47; A61K47/48; A61P35/00

Domestic Patent References:

WO1998018493A2	1998-05-07
WO1997014416A1	1997-04-24
WO1997012624A1	1997-04-10

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