SALT OF GLP-1 AGONIST, CRYSTAL FORM THEREOF, AND USE THEREOF IN MEDICINES

Title:

SALT OF GLP-1 AGONIST, CRYSTAL FORM THEREOF, AND USE THEREOF IN MEDICINES

Document Type and Number:

WIPO Patent Application WO/2023/124824

Kind Code:

A1

Abstract:

The present invention relates to a trihydroxymethyl aminomethane salt of a compound (S)-2-((6-((4-cyano-2-fluorobenzyl)oxy)-3',6'-dihydro-[2,4'-bipyridine]-1'(2'H)-yl)methyl)-1-(oxetane-2-ylmethyl)-1H thieno[2,3-d]imidazole-5-carboxylic acid, amorphous and crystal forms of the salt, a preparation method therefor, and a use thereof in pharmaceutical compositions and medicines.

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Inventors:

FAN JIANG (CN)
DOU YING (CN)
GONG ZHENG (CN)
ZHANG CHEN (CN)
LEI MING (CN)

Application Number:

PCT/CN2022/136872

Publication Date:

July 06, 2023

Filing Date:

December 06, 2022

Export Citation:

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Assignee:

HAISCO PHARMACEUTICAL GROUP CO LTD (CN)

International Classes:

C07D513/04; A61K31/497; A61P3/10

Domestic Patent References:

WO2021244645A1

2021-12-09

Foreign References:

CN113801136A	2021-12-17
CN110325530A	2019-10-11

Attorney, Agent or Firm:

WU, FENG & ZHANG (CN)

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