SALT OF LSD1 INHIBITOR AND A POLYMORPH THEREOF

Title:

SALT OF LSD1 INHIBITOR AND A POLYMORPH THEREOF

Document Type and Number:

WIPO Patent Application WO/2020/015745

Kind Code:

A1

Abstract:

Provided are a compound III serving as an LSD1 inhibitor and a polymorph thereof, as well as an application of the compound and the polymorph thereof in the preparation of drugs for treating LSD1-associated diseases.

Inventors:

ZHAO LELE (CN)
SUN JIANJUN (CN)
WU LINGYUN (CN)
CHEN SHUHUI (CN)

Application Number:

PCT/CN2019/096842

Publication Date:

January 23, 2020

Filing Date:

July 19, 2019

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Assignee:

MEDSHINE DISCOVERY INC (CN)

International Classes:

C07D271/06; A61K31/13; A61P35/00

Domestic Patent References:

WO2018137644A1	2018-08-02
WO2017195216A1	2017-11-16
WO2017184934A1	2017-10-26

Foreign References:

CN103857393A	2014-06-11
CN102947265A	2013-02-27
CN201810804068A	2018-07-20

Other References:

ADRIAN BIRD, NATURE, vol. 2007, pages 396 - 398
"Chinese Pharmacopoeia", 2015, article "Guiding Principles for Testing of Stability of API and Preparations"

Attorney, Agent or Firm:

SHANGHAI BESHINING LAW OFFICE (CN)

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