Login| Sign Up| Help| Contact|

Patent Searching and Data


Title:
SALT OF PHENYLPROPIONAMIDE DERIVATIVE AND PREPARATION METHOD THEREFOR
Document Type and Number:
WIPO Patent Application WO/2019/109934
Kind Code:
A1
Abstract:
The present invention provides a salt of a phenylpropionamide derivative and a preparation method therefor. The present invention specifically provides an acetate, hydrochloride, phosphate, citrate, benzoate, or fumarate of 4-amino-1-((2R,5R,8R,14R)-2-(4-aminobutyl)-8-benzyl-5-isobutyl-4,7,10-trioxo-14-phenyl-3,6,9,12-tetraazapentadecan-1-acyl)piperidine-4-carboxylic acid, and a preparation method therefor. The salt of the compound of formula (I) of the present invention has good stability, and the simple process thereof facilitates easy operation. The invention is better suited for clinical treatment.

Inventors:
WANG, Lin (No. 279 Wenjin Road, Economic and Technological Development Zone Minhang District, Shanghai 5, 200245, CN)
YE, Jingquan (No. 279 Wenjin Road, Economic and Technological Development Zone Minhang District, Shanghai 5, 200245, CN)
SHAO, Qiyun (No. 279 Wenjin Road, Economic and Technological Development Zone Minhang District, Shanghai 5, 200245, CN)
FENG, Jun (No. 279 Wenjin Road, Economic and Technological Development Zone Minhang District, Shanghai 5, 200245, CN)
HE, Feng (No. 279 Wenjin Road, Economic and Technological Development Zone Minhang District, Shanghai 5, 200245, CN)
CAO, Xiaoli (No. 7 Kunlunshan Road, Economic and Technological Development ZoneLianyungang, Jiangsu 7, 222047, CN)
MA, Yahui (No. 7 Kunlunshan Road, Economic and Technological Development ZoneLianyungang, Jiangsu 7, 222047, CN)
Application Number:
CN2018/119309
Publication Date:
June 13, 2019
Filing Date:
December 05, 2018
Export Citation:
Click for automatic bibliography generation   Help
Assignee:
JIANGSU HENGRUI MEDICINE CO., LTD. (No. 7 Kunlunshan Road, Economic and Technological Development ZoneLianyungang, Jiangsu 7, 222047, CN)
SHANGHAI HENGRUI PHARMACEUTICAL CO., LTD (No. 279 Wenjin Road, Economic and Technological Development Zone Minhang District, Shanghai 5, 200245, CN)
International Classes:
C07D295/18; A61K38/07; A61P29/00; C07K1/06; C07K5/107
Domestic Patent References:
WO2014089019A12014-06-12
Foreign References:
CN108290926A2018-07-17
US20160250277A12016-09-01
CN104271552A2015-01-07
US8809278B22014-08-19
Attorney, Agent or Firm:
SHANGHAI BESHINING LAW OFFICE (21st Floor, SFECO Mansion 681 Xiaomuqiao Road, Shanghai 2, 200032, CN)
Download PDF: