Title:
SALT OF PYRANOSE-SUBSTITUTED HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2019/154388
Kind Code:
A1
Abstract:
The present application relates to a salt of a pyranose-substituted heterocyclic compound, a preparation method therefor, and use thereof, and in particular, to an acid addition salt of a compound of formula (I) or a prodrug thereof, and further relates to D-glucuronate of a crystalline compound of formula (I) or a prodrug thereof. D-glucuronate of a compound of formula (II) has particular advantages in terms of crystallizability, subsequent purification, stability, formulation medicinal properties or quality control, and is most applicable for improving the formulation pharmaceutical properties, purity and quality control, as well as large-scale process development of such drugs.
Inventors:
ZHANG FEI (CN)
WANG PENG (CN)
ZHU LIN (CN)
SUN LILI (CN)
WANG PENG (CN)
ZHU LIN (CN)
SUN LILI (CN)
Application Number:
PCT/CN2019/074667
Publication Date:
August 15, 2019
Filing Date:
February 03, 2019
Export Citation:
Assignee:
YABAO PHARMACEUTICAL GROUP CO LTD (CN)
SUZHOU YABAO PHARMACEUTICAL R&D CO LTD (CN)
SUZHOU YABAO PHARMACEUTICAL R&D CO LTD (CN)
International Classes:
C07H19/04; A61K31/7042; A61P3/00
Foreign References:
| CN105636972A | 2016-06-01 | |||
| CN105593229A | 2016-05-18 | |||
| CN201810130672A | 2018-02-08 | |||
| CN201480054233A | 2014-10-28 |
Other References:
See also references of EP 3750905A4
Attorney, Agent or Firm:
PATENTSINO IP FIRM (CN)
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