Title:
SALT OF RADIOACTIVE FLUORINE-LABELED PRECURSOR COMPOUND
Document Type and Number:
WIPO Patent Application WO/2020/085238
Kind Code:
A1
Abstract:
In order to improve the stability of a precursor compound of a radioactive fluorine-labeled compound, the present invention provides a stabilized composition which contains, as a main component, a salt of a compound represented by formula (2). (In the formula, X1 represents a hydrogen atom or a halogen atom; X2 represents a fluorine atom or a nitrile group; and R1 represents a substituted or unsubstituted alkylsulfonyloxy group or a substituted or unsubstituted arylsulfonyloxy group.) By converting a compound represented by formula (2) into a salt, the compound represented by formula (2) is stabilized and is able to be stored for a long period of time.
Inventors:
ICHIKAWA HIROAKI (JP)
NAKAMURA SOICHI (JP)
OKUMURA YUKI (JP)
IZAWA AKIHIRO (JP)
NAKAMURA SOICHI (JP)
OKUMURA YUKI (JP)
IZAWA AKIHIRO (JP)
Application Number:
PCT/JP2019/041118
Publication Date:
April 30, 2020
Filing Date:
October 18, 2019
Export Citation:
Assignee:
NIHON MEDIPHYSICS CO LTD (JP)
International Classes:
A61K51/00; C07D401/14; A61K101/02
Domestic Patent References:
| WO2015199205A1 | 2015-12-30 | |||
| WO2019131458A1 | 2019-07-04 |
Foreign References:
| JP2013528161A | 2013-07-08 |
Attorney, Agent or Firm:
IDE Masatake (JP)
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