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Title:
SALTS OF HETEROCYCLIC INHIBITORS OF MONOCARBOXYLATE TRANSPORTER 4 FOR THE TREATMENT OF DISEASE
Document Type and Number:
WIPO Patent Application WO/2024/036243
Kind Code:
A3
Abstract:
Disclosed herein are new salts of substituted pyrazole compounds which inhibit the activity of the monocarboxylate transporter MCT4, or a mutant thereof. Also disclosed herein are compounds, pharmaceutical compositions, and methods of treatment of MCT4-mediated diseases, such as inflammatory disorders and proliferative disorders.

Inventors:
PARNELL MARK (US)
LAWSON JON (US)
MA WEI (US)
VARLASHKIN PETER (US)
TARCZYNSKI FRANK (US)
CARINO STEPHEN (US)
Application Number:
PCT/US2023/071973
Publication Date:
April 18, 2024
Filing Date:
August 10, 2023
Export Citation:
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Assignee:
VETTORE LLC (US)
International Classes:
A61K31/395; A61K31/215; A61K31/415; A61K31/4155; A61K31/33
Attorney, Agent or Firm:
STEVENS, Lauren (US)
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