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Patent Searching and Data


Title:
SAMPLE EVAPORATIVE CONTROL
Document Type and Number:
WIPO Patent Application WO2000067907
Kind Code:
A3
Abstract:
Devices and methods are provided using microfluidic devices for manipulating small volumes and determining a variety of chemical and physical events. The devices rely upon an opening to the atmosphere of a small volume in a zone, where a sample is placed in the zone where evaporation can occur. The zone is maintained in contact with a liquid medium that serves to replenish the liquid in the zone and maintain the composition of the mixture in the zone substantially constant. The diffusion of components in the zone is restricted during the course of the determination by the liquid flux into the zone.

Inventors:
SINGH SHARAT
ULLMAN EDWIN
GIBBONS IAN
BOONE TRAVIS
XIAO VIVIAN
BJORNSON TORLIEF
HOOPER HERBERT
Application Number:
PCT/US2000/012826
Publication Date:
February 08, 2001
Filing Date:
May 10, 2000
Export Citation:
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Assignee:
ACLARA BIOSCIENCES INC (US)
International Classes:
B01D57/02; B01J19/00; B01J19/16; G01N27/447; B01L3/00; B01L7/00; B03C5/00; C12M1/00; C12Q1/00; G01N1/34; G01N35/08; G01N37/00; C40B60/14; G01N35/00; (IPC1-7): B01L3/00; B01J19/16; G01N1/34
Domestic Patent References:
WO1998033052A11998-07-30
WO1995034374A21995-12-21
WO1999044746A11999-09-10
WO1997001085A11997-01-09
Foreign References:
US5593838A1997-01-14
US5223219A1993-06-29
US5334837A1994-08-02
US4659677A1987-04-21
US5558837A1996-09-24
US5785926A1998-07-28
US5766959A1998-06-16
US4960566A1990-10-02
Other References:
LITBORN ET AL.: "parallel reactions in open-chip based nanovials with compensation for solvent evaporation", ELECTROPHORESIS, 2000, de, pages 91 - 99, XP000934274
HANGHUI L ET AL: "Analytical chemistry in a drop", TRAC, TRENDS IN ANALYTICAL CHEMISTRY,GB,ANALYTICAL CHEMISTRY. CAMBRIDGE, vol. 15, no. 9, 1 October 1996 (1996-10-01), pages 468 - 475, XP004070366, ISSN: 0165-9936
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