Title:
SARM1 ENZYME ACTIVITY INHIBITOR AND APPLICATION THEREOF
Document Type and Number:
WIPO Patent Application WO/2023/025244
Kind Code:
A1
Abstract:
The present invention provides an application of an SARM1 enzyme activity inhibitor in the treatment of neurodegenerative diseases or neurological diseases or conditions. The present invention particularly provides a compound of formula I as an SARM1 enzyme activity inhibitor and a pharmaceutical composition thereof.
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Inventors:
NIU DEQIANG (CN)
ZHU ZHENDONG (CN)
FAN MING (CN)
LI XUKE (CN)
ZHU ZHENDONG (CN)
FAN MING (CN)
LI XUKE (CN)
Application Number:
PCT/CN2022/114815
Publication Date:
March 02, 2023
Filing Date:
August 25, 2022
Export Citation:
Assignee:
ARTIVILA BIOPHARMA (CN)
International Classes:
C07D471/04; A61K31/4353; A61K31/4985; A61P25/00; C07D487/04
Domestic Patent References:
| WO2020252229A2 | 2020-12-17 |
Foreign References:
| CN106565704A | 2017-04-19 |
Other References:
SIVAPPA RASAPALLI, SAMMETA VAMSHIKRISHNA REDDY, HUANG YANCHANG, GOLEN JAMES A., SAVINOV SERGEY N.: "Facile synthesis of 3-substituted imidazo[1,2- a ]pyridines through formimidamide chemistry", RSC ADVANCES, vol. 9, no. 51, 19 September 2019 (2019-09-19), pages 29659 - 29664, XP093039713, DOI: 10.1039/C9RA05841A
Attorney, Agent or Firm:
UNITALEN ATTORNEYS AT LAW (CN)
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