SARM1 ENZYME ACTIVITY INHIBITOR AND USE THEREOF IN NEURODEGENERATIVE DISEASES

Title:

SARM1 ENZYME ACTIVITY INHIBITOR AND USE THEREOF IN NEURODEGENERATIVE DISEASES

Document Type and Number:

WIPO Patent Application WO/2022/100570

Kind Code:

A1

Abstract:

Provided in the present disclosure is the use of a SARM1 enzyme activity inhibitor in the treatment of neurodegenerative diseases or neurological diseases or conditions, and in particular, provided in the present invention are a compound of formula (a) as a SARM1 enzyme activity inhibitor, and a pharmaceutical composition thereof.

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Inventors:

NIU DEQIANG (CN)
ZHU ZHENDONG (CN)
ZHAO YONGJUAN (CN)
LI WANHUA (CN)

Application Number:

PCT/CN2021/129518

Publication Date:

May 19, 2022

Filing Date:

November 09, 2021

Export Citation:

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Assignee:

ARTIVILA BIOPHARMA (CN)

International Classes:

A61K45/06; A61K31/055; A61K31/085; A61K31/10; A61K31/105; A61K31/167; A61K31/18; A61K31/4045; A61K31/41; A61K31/425; A61K31/433; A61K31/4439; A61K31/505; A61K31/506; A61K31/519; A61P21/00; A61P25/00; A61P25/02; A61P25/16; A61P25/28

Domestic Patent References:

WO2011151359A1	2011-12-08
WO2019236890A1	2019-12-12

Foreign References:

AU2006200668A1

2006-03-16

Attorney, Agent or Firm:

UNITALEN ATTORNEYS AT LAW (CN)

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