Title:
SARS-COV-2 ANTIGEN-BINDING PROTEINS AND USES THEREOF
Document Type and Number:
WIPO Patent Application WO/2022/099187
Kind Code:
A3
Abstract:
The present invention provides severe acute respiratory syndrome coronavirus (SARS-CoV), e.g., severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antigen- binding proteins, pharmaceutical compositions, and methods of use thereof to passively immunize and treat subjects having or at risk of having a SARS-CoV, e.g., SARS-CoV-2, infection.
Inventors:
ABRAHAM JONATHAN (US)
CLARK LARS (US)
CLARK SARAH (US)
CLARK LARS (US)
CLARK SARAH (US)
Application Number:
PCT/US2021/058593
Publication Date:
June 16, 2022
Filing Date:
November 09, 2021
Export Citation:
Assignee:
HARVARD COLLEGE (US)
International Classes:
A61P11/00; A61K39/42; A61P31/14
Domestic Patent References:
| WO2020169755A2 | 2020-08-27 |
Foreign References:
| US10822379B1 | 2020-11-03 |
Other References:
CAO YUNLONG; SU BIN; GUO XIANGHUA; SUN WENJIE; DENG YONGQIANG; BAO LINLIN; ZHU QINYU; ZHANG XU; ZHENG YINGHUI; GENG CHENYANG; CHAI: "Potent Neutralizing Antibodies against SARS-CoV-2 Identified by High-Throughput Single-Cell Sequencing of Convalescent Patients’ B Cells", CELL, ELSEVIER, AMSTERDAM NL, vol. 182, no. 1, 9 July 2020 (2020-07-09), Amsterdam NL , pages 73 - 84+16, XP086211425, ISSN: 0092-8674, DOI: 10.1016/j.cell.2020.05.025
ZHOU, G ET AL.: "Perspectives on therapeutic neutralizing antibodies against the Novel Coronavirus SARS-CoV-2.", INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES., vol. 16, no. 10, 15 March 2020 (2020-03-15), pages 1718 - 1723, XP055758309, DOI: 10.7150/ijbs.45123
ZHOU, G ET AL.: "Perspectives on therapeutic neutralizing antibodies against the Novel Coronavirus SARS-CoV-2.", INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES., vol. 16, no. 10, 15 March 2020 (2020-03-15), pages 1718 - 1723, XP055758309, DOI: 10.7150/ijbs.45123
Attorney, Agent or Firm:
ZACHARAKIS, Maria, Laccotripe et al. (US)
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