Title:
SCAFFOLD FOR BONE REGENERATION AND CONSTRUCTION METHOD THEREFOR
Document Type and Number:
WIPO Patent Application WO/2023/027247
Kind Code:
A1
Abstract:
The present invention relates to a scaffold for bone regeneration and a construction method therefor. The scaffold for bone regeneration of the present invention has grooves and ridges formed on one surface thereof and is equipped with a radial pattern to provide an environment suitable for cell adhesion and migration and bone differentiation, and thus can be effectively used as a material for bone regeneration.
Inventors:
SHIN KYOUNG JIN (KR)
KIM SUNG HO (KR)
KIM SUNG HO (KR)
Application Number:
PCT/KR2021/016318
Publication Date:
March 02, 2023
Filing Date:
November 10, 2021
Export Citation:
Assignee:
NANOBIOSYSTEM CO LTD (KR)
International Classes:
A61F2/28; A61F2/30; A61L27/14; A61L27/50
Foreign References:
| US20190380838A1 | 2019-12-19 |
Other References:
GWON YONGHYUN, PARK SUNHO, KIM WOOCHAN, HAN TAESEONG, KIM HYOSEONG, KIM JANGHO: "Radially patterned transplantable biodegradable scaffolds as topographically defined contact guidance platforms for accelerating bone regeneration", JOURNAL OF BIOLOGICAL ENGINEERING, vol. 15, no. 1, 1 December 2021 (2021-12-01), XP055965247, DOI: 10.1186/s13036-021-00263-8
YOON JEONG-KEE, KIM HONG NAM, BHANG SUK HO, SHIN JUNG-YOUN, HAN JIN, LA WAN-GEUN, JEONG GUN-JAE, KANG SEOKYUNG, LEE JU-RO, OH JAES: "Enhanced Bone Repair by Guided Osteoblast Recruitment Using Topographically Defined Implant", TISSUE ENGINEERING PART A, MARY ANN LIEBERT, US, vol. 22, no. 7-8, 1 April 2016 (2016-04-01), US , pages 654 - 664, XP055965245, ISSN: 1937-3341, DOI: 10.1089/ten.tea.2015.0417
DELLINGER JENNIFER G., JOSEPH CESARANO III, RUSSELL D. JAMISON: "Robotic deposition of model hydroxyapatite scaffolds with multiple architectures and multiscale porosity for bone tissue engineering", JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, vol. 82A, no. 2, 12 February 2007 (2007-02-12), pages 383 - 394, XP055965241, DOI: 10.1002/jbm.a.31072
CHEN, PENGFEI ET AL.: "Radially oriented collagen scaffold with SDF-1 promotes osteochondral repair by facilitating cell homing", BIOMATERIALS, vol. 39, 2015, pages 114 - 123, XP029102866, DOI: 10.1016/j.biomaterials.2014.10.049
See also references of EP 4166112A4
YOON JEONG-KEE, KIM HONG NAM, BHANG SUK HO, SHIN JUNG-YOUN, HAN JIN, LA WAN-GEUN, JEONG GUN-JAE, KANG SEOKYUNG, LEE JU-RO, OH JAES: "Enhanced Bone Repair by Guided Osteoblast Recruitment Using Topographically Defined Implant", TISSUE ENGINEERING PART A, MARY ANN LIEBERT, US, vol. 22, no. 7-8, 1 April 2016 (2016-04-01), US , pages 654 - 664, XP055965245, ISSN: 1937-3341, DOI: 10.1089/ten.tea.2015.0417
DELLINGER JENNIFER G., JOSEPH CESARANO III, RUSSELL D. JAMISON: "Robotic deposition of model hydroxyapatite scaffolds with multiple architectures and multiscale porosity for bone tissue engineering", JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, vol. 82A, no. 2, 12 February 2007 (2007-02-12), pages 383 - 394, XP055965241, DOI: 10.1002/jbm.a.31072
CHEN, PENGFEI ET AL.: "Radially oriented collagen scaffold with SDF-1 promotes osteochondral repair by facilitating cell homing", BIOMATERIALS, vol. 39, 2015, pages 114 - 123, XP029102866, DOI: 10.1016/j.biomaterials.2014.10.049
See also references of EP 4166112A4
Attorney, Agent or Firm:
LEECHAE INTELLECTUAL PROPERTY (KR)
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