Title:
SCREENING FOR INHIBITORS OF TCR-MHC INTERACTIONS
Document Type and Number:
WIPO Patent Application WO1996036881
Kind Code:
A3
Inventors:
BAROUCH DAN HUNG (GB)
VESSEY STEPHEN JOHN RUPERT (GB)
JAKOBSEN BENT KARSTEN (GB)
VESSEY STEPHEN JOHN RUPERT (GB)
JAKOBSEN BENT KARSTEN (GB)
Application Number:
PCT/GB1996/001165
Publication Date:
January 09, 1997
Filing Date:
May 16, 1996
Export Citation:
Assignee:
CANCER RES CAMPAIGN TECH (GB)
BAROUCH DAN HUNG (GB)
VESSEY STEPHEN JOHN RUPERT (GB)
JAKOBSEN BENT KARSTEN (GB)
BAROUCH DAN HUNG (GB)
VESSEY STEPHEN JOHN RUPERT (GB)
JAKOBSEN BENT KARSTEN (GB)
International Classes:
C07K14/725; C07K14/74; G01N33/569; (IPC1-7): G01N33/68; A61K38/17; C07K14/74; G01N33/569
Domestic Patent References:
| WO1995007707A1 | 1995-03-23 | |||
| WO1992016234A1 | 1992-10-01 |
Other References:
W. WILLIAMS ET AL.: "Modulation of T cell responses with MHC-derived peptides.", IMMUNOLOGICAL RESEARCH, vol. 11, no. 1, March 1992 (1992-03-01), BASEL, SWITZERLAND, pages 11 - 23, XP002015728
S. WEBER ET AL.: "Specific low-affinity recognition of major histocompatibility complex plus peptide by soluble T-cell receptor.", NATURE, vol. 356, 30 April 1992 (1992-04-30), LONDON, GB, pages 793 - 796, XP002008364
S. JAMESON ET AL.: "Clone-specific T cell receptor antagonists of major histocompatibility complex class I-restricted cytotoxic T cells.", THE JOURNAL OF EXPERIMENTAL MEDICINE, vol. 177, no. 6, 1 June 1993 (1993-06-01), NEW YORK, NY, USA, pages 1541 - 1550, XP000604978
J. MADRENAS ET AL.: "Zeta phosphorylation without ZAP-70 activation induced by TcR antagonists or partial agonists.", SCIENCE, vol. 267, no. 5197, 27 January 1995 (1995-01-27), WASHINGTON, DC, USA, pages 515 - 518, XP002015729
S. WEBER ET AL.: "Specific low-affinity recognition of major histocompatibility complex plus peptide by soluble T-cell receptor.", NATURE, vol. 356, 30 April 1992 (1992-04-30), LONDON, GB, pages 793 - 796, XP002008364
S. JAMESON ET AL.: "Clone-specific T cell receptor antagonists of major histocompatibility complex class I-restricted cytotoxic T cells.", THE JOURNAL OF EXPERIMENTAL MEDICINE, vol. 177, no. 6, 1 June 1993 (1993-06-01), NEW YORK, NY, USA, pages 1541 - 1550, XP000604978
J. MADRENAS ET AL.: "Zeta phosphorylation without ZAP-70 activation induced by TcR antagonists or partial agonists.", SCIENCE, vol. 267, no. 5197, 27 January 1995 (1995-01-27), WASHINGTON, DC, USA, pages 515 - 518, XP002015729
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