Title:
SCREENING MARKERS AND METHODS FOR NEURODEGENERATIVE DISORDERS
Document Type and Number:
WIPO Patent Application WO2001075165
Kind Code:
A3
Abstract:
The invention includes identification of specific markers, the elevation of which in central nervous tissue is associated with Alzheimer's Disease. The invention also includes improved assay methods for selecting compounds useful in reducing or preventing onset of the pathology with Alzheimer's Disease.
Inventors:
MCCONLOGUE LISA C (US)
GAMES KATE D (US)
YEDNOCK THEODORE A (US)
HUA TAN (US)
MESSERSMITH ELIZABETH (US)
BARD FREDERIQUE (US)
GAMES KATE D (US)
YEDNOCK THEODORE A (US)
HUA TAN (US)
MESSERSMITH ELIZABETH (US)
BARD FREDERIQUE (US)
Application Number:
PCT/US2001/010247
Publication Date:
October 31, 2002
Filing Date:
March 30, 2001
Export Citation:
Assignee:
ELAN PHARM INC (US)
MCCONLOGUE LISA C (US)
GAMES KATE D (US)
YEDNOCK THEODORE A (US)
HUA TAN (US)
MESSERSMITH ELIZABETH (US)
BARD FREDERIQUE (US)
MCCONLOGUE LISA C (US)
GAMES KATE D (US)
YEDNOCK THEODORE A (US)
HUA TAN (US)
MESSERSMITH ELIZABETH (US)
BARD FREDERIQUE (US)
International Classes:
C12Q1/68; C12Q1/6883; (IPC1-7): C12Q1/68; A01K67/027
Domestic Patent References:
| WO1996040896A1 | 1996-12-19 | |||
| WO1996006927A1 | 1996-03-07 |
Other References:
GAMES D ET AL: "ALZHEIMER-TYPE NEUROPATHOLOGY IN TRANSGENIC MICE OVEREXPRESSING V717F BETA-AMYLOID PRECURSOR PROTEIN", NATURE, MACMILLAN JOURNALS LTD. LONDON, GB, vol. 373, no. 6514, 9 February 1995 (1995-02-09), pages 523 - 527, XP000602050, ISSN: 0028-0836
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