Title:
SCREENING METHOD OF PLATELET PRODUCTION PROMOTER
Document Type and Number:
WIPO Patent Application WO/2017/131228
Kind Code:
A1
Abstract:
A screening method of a platelet production promoter is provided which involves a step in which a candidate substance that significantly increases the expression of TUBB1 is selected as a platelet production promoter.
Inventors:
ETO KOJI (JP)
SEO HIDEYA (JP)
OTA AKIRA (JP)
ITO YUKITAKA (JP)
HAZAMA YASUKO (JP)
SEO HIDEYA (JP)
OTA AKIRA (JP)
ITO YUKITAKA (JP)
HAZAMA YASUKO (JP)
Application Number:
PCT/JP2017/003169
Publication Date:
August 03, 2017
Filing Date:
January 30, 2017
Export Citation:
Assignee:
UNIV KYOTO (JP)
MEGAKARYON CORP (JP)
MEGAKARYON CORP (JP)
International Classes:
C12N15/09; C12N5/078; C12Q1/02; C12Q1/68
Domestic Patent References:
| WO2014168255A1 | 2014-10-16 | |||
| WO2008078453A1 | 2008-07-03 | |||
| WO2016143836A1 | 2016-09-15 | |||
| WO2012157586A1 | 2012-11-22 | |||
| WO2013051625A1 | 2013-04-11 | |||
| WO2011034073A1 | 2011-03-24 | |||
| WO2011034073A1 | 2011-03-24 | |||
| WO2012157586A1 | 2012-11-22 | |||
| WO2014123242A1 | 2014-08-14 | |||
| WO2010134526A1 | 2010-11-25 |
Other References:
HIDEYA SEO ET AL.: "CRISPR/Cas9 Genom Henshu Gijutsu o Oyo shita Kyokakukyu Seijuku Sokushin'yaku Tansaku System no Kakuritsu", JOURNAL OF THE JAPANESE SOCIETY FOR REGENERATIVE MEDICINE, REGENERATIVE MEDICINE SPECIAL EXTRA ISSUE, vol. 15, 1 February 2016 (2016-02-01), pages 219, XP009513406
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KIM, Y. G. ET AL., PROC. NATL. ACAD. SCI. USA, vol. 93, 1996, pages 1156 - 1160
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PROC. NATL. ACAD. SCI. USA, vol. 100, 2003, pages 211 - 216
NAKAMURA S. ET AL., CELL STEM CELL, vol. 14, 2014, pages 535 - 548
NAKAMURA ET AL., CELL STEM CELL, 2014
OKITA K ET AL., STEM CELLS, vol. 31, no. 3, 2013, pages 458 - 466
CHEMICAL ABSTRACTS, Columbus, Ohio, US; abstract no. 301305-73-7
CHEMICAL ABSTRACTS, Columbus, Ohio, US; abstract no. 1243243-89-1
TAKAYAMA, N. ET AL., BLOOD, vol. 111, 2008, pages 5298 - 5306
NG ET AL., PROC. NATL. ACAD. SCI., vol. 111, no. 16, 2014, pages 5884 - 5889
NISHIMURA ET AL., JCB, vol. 209, 2015, pages 327 - 328
HIRATA ET AL., J. CLIN. INVEST., vol. 123, no. 9, pages 3802 - 3814
CONG, L. ET AL., SCIENCE, vol. 339, 2013, pages 819 - 823
CERMAK, T. ET AL., NUCLEIC ACIDS RES., vol. 39, 2011, pages e82
KIM, Y. G. ET AL., PROC. NATL. ACAD. SCI. USA, vol. 93, 1996, pages 1156 - 1160
OGURA ET AL., SAISEI IGAKU [REGENERATIVE MEDICINE, vol. 6, no. 4, pages 26 - 32
JESUS GILL ET AL., NATURE REVIEWS MOLECULAR CELL BIOLOGY, vol. 7, 2006, pages 667 - 677
PROC. NATL. ACAD. SCI. USA, vol. 100, 2003, pages 211 - 216
NAKAMURA S. ET AL., CELL STEM CELL, vol. 14, 2014, pages 535 - 548
NAKAMURA ET AL., CELL STEM CELL, 2014
OKITA K ET AL., STEM CELLS, vol. 31, no. 3, 2013, pages 458 - 466
CHEMICAL ABSTRACTS, Columbus, Ohio, US; abstract no. 301305-73-7
CHEMICAL ABSTRACTS, Columbus, Ohio, US; abstract no. 1243243-89-1
Attorney, Agent or Firm:
INABA, Yoshiyuki et al. (JP)
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