SEALING HYDROGEL, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF

Title:

SEALING HYDROGEL, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF

Document Type and Number:

WIPO Patent Application WO/2022/016664

Kind Code:

A1

Abstract:

A sealing hydrogel, a preparation method therefor and an application thereof, relating to the technical field of polymer materials. Raw materials for preparing the sealing hydrogel comprise a first component and a second component. The first component comprises a compound A and a compound B. The compound A is a multiarm polyethylene glycol derivative, and the compound B is polyarm copolyester of glycidyl isopropyl ether and ethyl glycidyl ether. The second component comprises oligopeptide or a derivative thereof. By means of the selection of a high molecular weight compound in gel components and the coordination of the first component and the second component, the swelling ratio of the hydrogel can be effectively reduced.

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Inventors:

LENG HONGFEI (CN)
XU XIAOYU (CN)
TAO XIUMEI (CN)

Application Number:

PCT/CN2020/112194

Publication Date:

January 27, 2022

Filing Date:

August 28, 2020

Export Citation:

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Assignee:

NKD PHARM CO LTD (CN)

International Classes:

A61L31/06; A61L31/04; A61L31/14; A61L31/16; C08J3/075; C08L5/08; C08L67/00; C08L71/02

Foreign References:

CN105169469A	2015-12-23
CN110433344A	2019-11-12
CN106913902A	2017-07-04
CN105778124A	2016-07-20
CN110643057A	2020-01-03
KR20020089772A	2002-11-30
US20200206367A1	2020-07-02

Other References:

JOHNSTON TREVOR G., FELLIN CHRISTOPHER R., CARIGNANO ALBERTO, NELSON ALSHAKIM: "Poly(alkyl glycidyl ether) hydrogels for harnessing the bioactivity of engineered microbes", FARADAY DISCUSSIONS, ROYAL SOCIETY OF CHEMISTRY, CAMBRIDGE, GB, vol. 219, 30 October 2019 (2019-10-30), GB , pages 58 - 72, XP055889210, ISSN: 1359-6640, DOI: 10.1039/C9FD00019D
See also references of EP 4186537A4

Attorney, Agent or Firm:

CN-KNOWHOW INTELLECTUAL PROPERTY AGENT LIMITED (CN)

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