Title:
SELECTIVE ANALYTE DETECTION AND QUANTITATION IN MASS SPECTROMETRY USING MULTIPLICATION OF HIGH RESOLUTION SIGNAL CHANNELS
Document Type and Number:
WIPO Patent Application WO/2013/138326
Kind Code:
A3
Abstract:
Systems and methods for detecting and identifying the presence of an analyte in a sample using a high resolution mass spectrometry system. In an implementation the method includes ionizing an analyte to yield ions, passing the ions into the mass spectrometry system, fragmenting a portion of the ions passed into the mass spectrometry system such that there may be both fragment ions and non-fragmented ions passing through the system, identifying a first signal associated with the fragment ions, identifying a second signal associated with the non- fragmented ions, multiplying the first signal with the second signal to derive a third signal, and analyzing the third signal to identify a peak that is indicative of the presence of an analyte.
Inventors:
PATRICK JEFFREY S (US)
SIEK KEVIN (US)
SIEK KEVIN (US)
Application Number:
PCT/US2013/030492
Publication Date:
August 28, 2014
Filing Date:
March 12, 2013
Export Citation:
Assignee:
LECO CORP (US)
International Classes:
H01J49/00; G01N30/72
Domestic Patent References:
| WO2011027131A1 | 2011-03-10 | |||
| WO2011058381A1 | 2011-05-19 |
Attorney, Agent or Firm:
O'BRIEN, Jonathan, P. et al. (350 East Michigan Avenue Suite 30, Kalamazoo MI, US)
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