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Patent Searching and Data


Title:
SELF-ASSEMBLY FOR ACTIVATING IMMUNITY
Document Type and Number:
WIPO Patent Application WO/2020/045570
Kind Code:
A1
Abstract:
Provided are: a novel compound that forms a self-assembly; the self-assembly; production methods for the compound and the self-assembly; and pharmaceutical use of the compound and the self-assembly. The compound is represented by formula (I) [in the formula, Rx represents H or a group represented by formula (II), Ry represents H or a group represented by formula (III), R1, R2, R3, and R4 each independently represent H, C1-6 alkyl, or C1-6 haloalkyl, a wavy line represents a binding site, and n represents an integer of 1-12]. The self-assembly is formed by the composition. The production methods are for the compound and the self-assembly, and the pharmaceutical use are for the compound and the self-assembly.

Inventors:
UESUGI MOTONARI (JP)
VU HUE T (JP)
YOSHIDA HIROKI (JP)
NODA NAOTAKA (JP)
JIN SHUYU (JP)
YAMASAKI SHO (JP)
SHIMANE TORU (JP)
ISHII KEN (JP)
HIOKI KOU (JP)
Application Number:
PCT/JP2019/033920
Publication Date:
March 05, 2020
Filing Date:
August 29, 2019
Export Citation:
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Assignee:
UNIV KYOTO (JP)
UNIV OSAKA (JP)
International Classes:
A61K38/07; A61K31/575; A61K39/00; A61K39/39; A61K47/62; A61P9/12; A61P25/28; A61P31/00; A61P35/00; A61P37/02; A61P37/04; A61P37/08; C07J9/00; C07K5/02
Domestic Patent References:
WO2015079952A12015-06-04
Foreign References:
US20050222115A12005-10-06
US20060003974A12006-01-05
Other References:
SALUNKE, DEEPAK B. ET AL.: "New steroidal dimers with antifungal and antiproliferative activity", JOURNAL OF MEDICINAL CHEMISTRY, vol. 47, no. 6, 2004, pages 1591 - 1594, XP055697288
LI, YAN ET AL.: "Design, synthesis and antitumor activity of dimeric bile acid-amino acid conjugates", LETT IN ORG CHEM, vol. 4, no. 6, 2007, pages 414 - 418, XP055697317
OYAMA, SHOHEI ET AL.: "The necessity and safety of vaccine adjuvant", JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE, vol. 234, no. 3, 2010, pages 217 - 221
Attorney, Agent or Firm:
YAMAO, Norihito et al. (JP)
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