Title:
SEMI-SOLID AND VISCOUS LIQUID NASAL FORMULATIONS OF CANNABINOIDS
Document Type and Number:
WIPO Patent Application WO/2017/208072
Kind Code:
A3
Abstract:
Cannabinoid containing pharmaceutical compositions suitable for nasal administration are disclosed. The compositions comprise the aforementioned cannabinoids and excipients selected such that the compositions are semi-solid or viscous liquids. In preferred embodiments, the cannabinoid is A9-tetrahydrocannabinol (THC) or cannabidiol (CBD). The excipients are preferably a mixture of an oily vehicle (such as castor oil or sucrose acetate isobutyrate) and a wetting agent/surfactant (such as oleoyl polyoxylglycerides). The compositions may further comprise thickeners (such as silicon dioxide) and other excipients. Methods for manufacturing and administering the compositions are disclosed, as well as methods for using the compositions in the treatment of disorders commonly known to be affected by cannabinoids.
Inventors:
BRYSON NATHAN (CA)
SHARMA AVINASH CHANDER (CA)
SHARMA AVINASH CHANDER (CA)
Application Number:
PCT/IB2017/000759
Publication Date:
January 11, 2018
Filing Date:
June 02, 2017
Export Citation:
Assignee:
ACERUS PHARMACEUTICAL CORP (CA)
International Classes:
A61K9/10; A61K9/00; A61K31/05; A61K47/44; A61P25/00; A61P29/00; C07C39/23
Domestic Patent References:
| WO2002064109A2 | 2002-08-22 | |||
| WO1999032107A1 | 1999-07-01 | |||
| WO2012156820A1 | 2012-11-22 |
Other References:
See also references of EP 3478270A4
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