Title:
SENSING METHOD
Document Type and Number:
WIPO Patent Application WO/2016/076019
Kind Code:
A1
Abstract:
Provided is a technique for measuring with high reliability when sensing an object to be sensed in a sample solution on the basis of frequency variations of a crystal resonator (4). A sensing method causes the object to be sensed to adhere to the crystal resonator (4) to measure the amount of an object to be sensed according to frequency variations based on the result of the addition of mass, wherein an oscillation frequency measurement is taken before the measurement region is set as a liquid phase and thereafter the sample solution is supplied to the measurement region. Thereafter, the liquid components in the measurement region are removed and the oscillation frequency is measured as a gas phase so as to measure the difference in frequency with the oscillation frequency before supplying the sample solution to the measurement region. Therefore, because the piezoelectric resonator oscillates in the gas phase, an error in the oscillation frequency or a reduction in the variation amount of the oscillation frequency caused by the crystal resonator (4) coming into contact with the liquid phase, is suppressed and the object to be sensed can be sensed with high accuracy.
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Inventors:
SHINOBU WAKAKO (JP)
Application Number:
PCT/JP2015/077017
Publication Date:
May 19, 2016
Filing Date:
September 25, 2015
Export Citation:
Assignee:
NIHON DEMPA KOGYO CO (JP)
International Classes:
G01N5/02
Domestic Patent References:
| WO2009117013A1 | 2009-09-24 |
Foreign References:
| JP2008512673A | 2008-04-24 | |||
| JP2006275864A | 2006-10-12 | |||
| JP2008107167A | 2008-05-08 |
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