Title:
SGC STIMULATORS
Document Type and Number:
WIPO Patent Application WO/2018/089330
Kind Code:
A8
Abstract:
The present disclosure relates to stimulators of soluble guanylate cyclase (sGC), pharmaceutical formulations comprising them and their uses thereof, alone or in combination with one or more additional agents, for treating various diseases, wherein an increase in the concentration of nitric oxide (NO) and/or an increase in the concentration of cyclic Guanosine Monophosphate (cGMP) might be desirable. Various compounds are disclosed, including those of Formula (I).
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Inventors:
RENNIE GLEN (US)
BARDEN TIMOTHY (US)
LEE THOMAS (US)
IYENGAR RAJESH (US)
NAKAI TAKASHI (US)
MERMERIAN ARA (US)
JIA JAMES (US)
IYER KARTHIK (US)
IM G-YOON (US)
RENHOWE PAUL (US)
JUNG JOON (US)
GERMANO PETER (US)
TANG KIM (US)
BARDEN TIMOTHY (US)
LEE THOMAS (US)
IYENGAR RAJESH (US)
NAKAI TAKASHI (US)
MERMERIAN ARA (US)
JIA JAMES (US)
IYER KARTHIK (US)
IM G-YOON (US)
RENHOWE PAUL (US)
JUNG JOON (US)
GERMANO PETER (US)
TANG KIM (US)
Application Number:
PCT/US2017/060305
Publication Date:
March 28, 2019
Filing Date:
November 07, 2017
Export Citation:
Assignee:
IRONWOOD PHARMACEUTICALS INC (US)
International Classes:
C07D403/04; A61K31/4353; A61K31/506; A61K31/519; A61K31/5377; A61P25/02; A61P25/16; A61P25/18; A61P25/22; A61P25/28; A61P25/30; A61P25/32; A61P25/36; C07D403/14; C07D407/14; C07D487/04
Attorney, Agent or Firm:
DAVIS, Steven, G. et al. (US)
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