Title:
SIGNAL SEQUENCES FOR NUCLEIC ACID VACCINES
Document Type and Number:
WIPO Patent Application WO/2023/214082
Kind Code:
A3
Abstract:
Provided herein is a nucleic acid (e.g., messenger RNA) vaccine encoding at least one antigenic prokaryotic polypeptide linked to one or both of a viral secretion signal peptide and a transmembrane domain. Also provided are methods of vaccination against a prokaryotic infection with the nucleic acid described herein.
Inventors:
GIRERD-CHAMBAZ YVES (FR)
PAVOT VINCENT (FR)
CIVAT CÉLINE (FR)
PION CORINNE (FR)
PAVOT VINCENT (FR)
CIVAT CÉLINE (FR)
PION CORINNE (FR)
Application Number:
PCT/EP2023/062066
Publication Date:
December 28, 2023
Filing Date:
May 05, 2023
Export Citation:
Assignee:
SANOFI SA (FR)
International Classes:
A61K39/02; A61P31/04; C12N15/82
Domestic Patent References:
| WO2010005474A1 | 2010-01-14 | |||
| WO2020216844A1 | 2020-10-29 |
Foreign References:
| US20200038499A1 | 2020-02-06 |
Other References:
KAMP HEATHER D. ET AL: "Design of a broadly reactive Lyme disease vaccine", vol. 5, no. 1, 1 December 2020 (2020-12-01), XP055950437, Retrieved from the Internet DOI: 10.1038/s41541-020-0183-8
Attorney, Agent or Firm:
ERNEST GUTMANN - YVES PLASSERAUD SAS (FR)
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