Title:
SILOXANE COMPOUND AND METHOD FOR PRODUCING SAME
Document Type and Number:
WIPO Patent Application WO/2019/107117
Kind Code:
A1
Abstract:
[Problem] To provide: a siloxane compound which is a polymerizable monomer having a polysiloxane structure, has a purity and high oxygen permeability suitable for an ophthalmic device, and has sufficient compatibility with other polymerizable monomers; and a method for producing said siloxane compound. [Solution] The present invention provides a highly pure siloxane compound having a glycerol (meth)acrylate, wherein the siloxane compound is obtained by subjecting a carboxylic acid and an epoxy-modified siloxane compound having a bulky substituent on silicon atoms in a polysiloxane to an addition reaction to suppress side reactions derived from generated hydroxyl groups or side reactions between the carboxylic acid and the siloxane moiety. Furthermore, a siloxane compound containing a bulky substituent group-terminated glycerol (meth)acrylate is used as a monomer to thereby provide a copolymer which has excellent solubility in solvents such as acetone compared to (co)polymers obtained using SiGMA as a monomer. That is, the present invention provides: a method for producing a (meth)acryl group-containing siloxane compound, the method comprising a step in which an epoxy-modified siloxane compound which is represented by formula (2) and has a bulky substituent on silicon atoms in a polysiloxane is reacted with a methacrylic acid or acrylic acid to obtain a siloxane compound which is represented by formula (I) and has a glycerol (meth)acrylate; a (co)polymer obtained from said siloxane compound; and an ophthalmic device.
Inventors:
OKAMURA KAORU (JP)
Application Number:
PCT/JP2018/041706
Publication Date:
June 06, 2019
Filing Date:
November 09, 2018
Export Citation:
Assignee:
SHINETSU CHEMICAL CO (JP)
International Classes:
C07F7/08; C08F30/08
Domestic Patent References:
| WO2009085297A2 | 2009-07-09 | |||
| WO2009085300A2 | 2009-07-09 | |||
| WO2017188046A1 | 2017-11-02 |
Foreign References:
| JP2010510316A | 2010-04-02 | |||
| JP2009542850A | 2009-12-03 | |||
| JP2008274278A | 2008-11-13 | |||
| JPS5455455A | 1979-05-02 | |||
| JPS5622325A | 1981-03-02 | |||
| JP2004182724A | 2004-07-02 | |||
| JP2006169140A | 2006-06-29 |
Other References:
See also references of EP 3719025A4
SHIMIZU, N. ET AL.: "A Quantitative Scale for the Structural Effect on Reactivity toward Nucleophilic Displacement at Silicon", CHEMISTRY LETTERS, vol. 21, no. 7, 1992, pages 1263 - 1266, XP009020659, DOI: 10.1246/cl.1992.1263
SHIMIZU, N. ET AL.: "Prediction of Structural Effects of Trialkyl Groups on Reactivity toward Nucleophilic Displacement at Silicon", CHEMISTRY LETTERS, vol. 22, no. 10, 1993, pages 1807 - 1810
SHIMIZU, N. ET AL.: "A Quantitative Scale for the Structural Effect on Reactivity toward Nucleophilic Displacement at Silicon", CHEMISTRY LETTERS, vol. 21, no. 7, 1992, pages 1263 - 1266, XP009020659, DOI: 10.1246/cl.1992.1263
SHIMIZU, N. ET AL.: "Prediction of Structural Effects of Trialkyl Groups on Reactivity toward Nucleophilic Displacement at Silicon", CHEMISTRY LETTERS, vol. 22, no. 10, 1993, pages 1807 - 1810
Attorney, Agent or Firm:
MATSUI Mitsuo et al. (JP)
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