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Title:
SINGLE-DOMAIN ANTIBODIES AND VARIANTS THEREOF AGAINST CTLA-4
Document Type and Number:
WIPO Patent Application WO/2018/068201
Kind Code:
A1
Abstract:
The present application provides constructs comprising a single-domain antibody (sdAb) moiety that specifically recognizes CTLA-4. Also provided are methods of making and using these constructs.

Inventors:
ZHANG YAFENG (CN)
WU SHU (CN)
YANG SHUAI (CN)
CHOU CHUAN-CHU (US)
Application Number:
PCT/CN2016/101777
Publication Date:
April 19, 2018
Filing Date:
October 11, 2016
Export Citation:
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Assignee:
NANJING LEGEND BIOTECH CO LTD (CN)
International Classes:
A61K39/395; C07K16/28; A61P31/00; A61P35/00; C12N5/10; C12N15/13; C12N15/63
Domestic Patent References:
WO2010097597A12010-09-02
WO2001014424A22001-03-01
Foreign References:
CN105754990A2016-07-13
Attorney, Agent or Firm:
CHENG & PENG INTELLECTUAL PROPERTY LAW OFFICE (CN)
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