Title:
SINGLE NANOPARTICLE HAVING A NANOGAP BETWEEN A CORE MATERIAL AND A SHELL MATERIAL, AND MANUFACTURING METHOD THEREOF
Document Type and Number:
WIPO Patent Application WO/2012/070893
Kind Code:
A2
Abstract:
The present invention relates to nanoparticles including a core and a shell surrounding the core between which a nanogap is formed, and a manufacturing method thereof, which can be usefully used for Raman analysis because they have a very high signal-amplifying effect and reproducibility by means of a plasmonic-coupling effect caused by the nanogap. Also, the present invention provides a method for detecting an analyte using the nanoparticles, and a kit for detecting an analyte containing the nanoparticles.
Inventors:
SUH YUNG DOUG (KR)
NAM JWA MIN (KR)
LIM DONG KWON (KR)
JEON KI SEOK (KR)
NAM JWA MIN (KR)
LIM DONG KWON (KR)
JEON KI SEOK (KR)
Application Number:
PCT/KR2011/009031
Publication Date:
May 31, 2012
Filing Date:
November 24, 2011
Export Citation:
Assignee:
KOREA RES INST CHEM TECH (KR)
SNU R&DB FOUNDATION (KR)
SUH YUNG DOUG (KR)
NAM JWA MIN (KR)
LIM DONG KWON (KR)
JEON KI SEOK (KR)
SNU R&DB FOUNDATION (KR)
SUH YUNG DOUG (KR)
NAM JWA MIN (KR)
LIM DONG KWON (KR)
JEON KI SEOK (KR)
International Classes:
G01N33/53; A61K49/06; G01N21/63; G01N33/58
Foreign References:
| US6002471A | 1999-12-14 | |||
| US6040191A | 2000-03-21 | |||
| US6149868A | 2000-11-21 | |||
| US6174677B1 | 2001-01-16 | |||
| US6313914B1 | 2001-11-06 | |||
| US5306403A | 1994-04-26 |
Other References:
SCIENCE, vol. 275, no. 5303, 1997, pages 1102
PHYS REV LETT, vol. 78, no. 9, 1997, pages 1667
SCIENCE, vol. 297, 2002, pages 1536
J PHYS CHEM B, vol. 106, no. 2, 2002, pages 311
SCIENCE, vol. 321, 2008, pages 388
L. BRUS ET AL., JACS, 2002
FELDHEIM, THE ELECTROCHEMICAL SOCIETY INTERFACE, 2001, pages 22 - 25
S. J. HURST; A. K. R. LYTTON-JEAN; C. A. MIRKIN, ANAL. CHEM., vol. 78, 2006, pages 8313
P. B. JOHNSON; R. W. CHRISTY, PHYS. REV. B., vol. 6, 1972, pages 4370 - 4379
P.G. ETCHEGOIN; E. C. LE RU; M. MEYER, J. CHEM. PHYS., vol. 125, 2006, pages 164705
G. RONG; A. NAJMAIE; J. E. SIPE; S. M. WEISS, BIOSENSORS AND BIOELECTRONICS, vol. 23, 2008, pages 1572 - 1576
SJ HURST; AKR LYTTON-JEAN; CA MIRKIN, ANAL. CHEM., vol. 78, 2006, pages 8313
Z. WANG; J. ZHANG; JM EKMAN; PJA KENIS; Y. LU, NANO LETT., 2010
A. SCHIMANSKI; E. FREISINGER; A. ERXLEBEN; B. LIPPERT, INORGANICA CHIMICA ACTA, vol. 283, 1998, pages 223
KR BROWN; MJ NATAN, LANGMUIR, vol. 14, 1998, pages 726
Z. MA; S. SUI, ANGEW CHEM. INT ED, vol. 41, 2002, pages 2176
WUSTHOLZ, K. L. ET AL.: "Structure-activity relationships in gold nanoparticle dimers and trimers for surface-enhanced Raman spectroscopy", J. AM. CHEM. SOC., vol. 132, 2010, pages 10903 - 10910
SONNEFRAUD, Y. ET AL.: "Experimental realization of subradiant, superradiant, and fano resonance in ring/disk plasmonic nanocavities", ACS NANO, vol. 4, 2010, pages 1664 - 1670
D. K. LIM; K. S. JEON; H. M. KIM; J. M. NAM; Y. D. SUH, NATURE MATER., vol. 9, 2010, pages 60
P. ZHANG; Y. GUO, J. AM. CHEM. SOC., vol. 131, 2009, pages 3808
C. L. ZAVALETA ET AL., PROC. NATL. ACAD. SCI. USA, vol. 116, 2009, pages 13511
K. FAULDS; W. E. SMITH; D. GRAHAM, ANAL. CHEM., vol. 76, 2004, pages 412
See also references of EP 2645104A4
PHYS REV LETT, vol. 78, no. 9, 1997, pages 1667
SCIENCE, vol. 297, 2002, pages 1536
J PHYS CHEM B, vol. 106, no. 2, 2002, pages 311
SCIENCE, vol. 321, 2008, pages 388
L. BRUS ET AL., JACS, 2002
FELDHEIM, THE ELECTROCHEMICAL SOCIETY INTERFACE, 2001, pages 22 - 25
S. J. HURST; A. K. R. LYTTON-JEAN; C. A. MIRKIN, ANAL. CHEM., vol. 78, 2006, pages 8313
P. B. JOHNSON; R. W. CHRISTY, PHYS. REV. B., vol. 6, 1972, pages 4370 - 4379
P.G. ETCHEGOIN; E. C. LE RU; M. MEYER, J. CHEM. PHYS., vol. 125, 2006, pages 164705
G. RONG; A. NAJMAIE; J. E. SIPE; S. M. WEISS, BIOSENSORS AND BIOELECTRONICS, vol. 23, 2008, pages 1572 - 1576
SJ HURST; AKR LYTTON-JEAN; CA MIRKIN, ANAL. CHEM., vol. 78, 2006, pages 8313
Z. WANG; J. ZHANG; JM EKMAN; PJA KENIS; Y. LU, NANO LETT., 2010
A. SCHIMANSKI; E. FREISINGER; A. ERXLEBEN; B. LIPPERT, INORGANICA CHIMICA ACTA, vol. 283, 1998, pages 223
KR BROWN; MJ NATAN, LANGMUIR, vol. 14, 1998, pages 726
Z. MA; S. SUI, ANGEW CHEM. INT ED, vol. 41, 2002, pages 2176
WUSTHOLZ, K. L. ET AL.: "Structure-activity relationships in gold nanoparticle dimers and trimers for surface-enhanced Raman spectroscopy", J. AM. CHEM. SOC., vol. 132, 2010, pages 10903 - 10910
SONNEFRAUD, Y. ET AL.: "Experimental realization of subradiant, superradiant, and fano resonance in ring/disk plasmonic nanocavities", ACS NANO, vol. 4, 2010, pages 1664 - 1670
D. K. LIM; K. S. JEON; H. M. KIM; J. M. NAM; Y. D. SUH, NATURE MATER., vol. 9, 2010, pages 60
P. ZHANG; Y. GUO, J. AM. CHEM. SOC., vol. 131, 2009, pages 3808
C. L. ZAVALETA ET AL., PROC. NATL. ACAD. SCI. USA, vol. 116, 2009, pages 13511
K. FAULDS; W. E. SMITH; D. GRAHAM, ANAL. CHEM., vol. 76, 2004, pages 412
See also references of EP 2645104A4
Attorney, Agent or Firm:
SON, MIN (KR)
손민 (KR)
손민 (KR)
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