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Title:
SIRNA MOLECULE FOR REGULATING ANGPTL3 GENE ACTIVITY
Document Type and Number:
WIPO Patent Application WO/2024/032608
Kind Code:
A1
Abstract:
Provided are a small interfering RNA (siRNA) for inhibiting the expression of angiopoietin-like 3 (ANGPTL3) protein in a cell, a cell comprising the siRNA, and a method for treating a disease or symptom associated with ANGPTL3 expression in a subject using the siRNA or the cell.

Inventors:
HUANG JINYU (CN)
YUE MING (CN)
Application Number:
PCT/CN2023/111739
Publication Date:
February 15, 2024
Filing Date:
August 08, 2023
Export Citation:
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Assignee:
SHANGHAI RONA THERAPEUTICS CO LTD (CN)
International Classes:
A61K31/713; C12N15/113; A61P3/06
Domestic Patent References:
WO2022068923A12022-04-07
WO2022079222A12022-04-21
WO2020099482A22020-05-22
Foreign References:
CN111343994A2020-06-26
US20130023579A12013-01-24
US20180087054A12018-03-29
Attorney, Agent or Firm:
LIU , SHEN & ASSOCIATES (CN)
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