Title:
SKIN COLLAGEN PRODUCTION PROMOTER
Document Type and Number:
WIPO Patent Application WO/2012/111187
Kind Code:
A1
Abstract:
[Problem] To provide a medicine, cosmetic and supplement comprising food constituents or nutrients which have been used extensively as food and are safe, and having skin collagen production promoting effects. [Solution] The skin collagen production promoter according to the present invention includes menaquinone-7 as an active ingredient. This skin collagen production promoter is administered transdermally or orally, and is provided as a medicine, cosmetic and supplement.
Inventors:
SATO TOSHIRO (JP)
KAWAHARA RUMI (JP)
KAMO SHUICHI (JP)
KAWAHARA RUMI (JP)
KAMO SHUICHI (JP)
Application Number:
PCT/JP2011/068123
Publication Date:
August 23, 2012
Filing Date:
August 09, 2011
Export Citation:
Assignee:
J OIL MILLS INC (JP)
SATO TOSHIRO (JP)
KAWAHARA RUMI (JP)
KAMO SHUICHI (JP)
SATO TOSHIRO (JP)
KAWAHARA RUMI (JP)
KAMO SHUICHI (JP)
International Classes:
A61K31/122; A61K8/67; A61P17/00; A61P37/08; A61P39/00; A61P43/00; A61Q19/00; A61Q19/08
Domestic Patent References:
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Other References:
AICHI-KEN SANGYO GIJUTSU KENKYUSHO KENKYU HOKOKU, no. 2, 2003, pages 132 - 133, XP008158239
VITAMIN, vol. 80, no. 4, 2006, pages 203, XP008158244
IDE, Y. ET AL.: "Inhibition of matrix metalloproteinase expression by menatetrenone, a vitamin K2 analogue", ONCOL. REP., vol. 22, 2009, pages 599 - 604, XP008158201
BOND, M. ET AL.: "Nuclear factor kB activity is essential for matrix metalloproteinase-1 and -3 upregulation in rabit dermal fibroblasts", BIOCHEM. BIOPHYS. RES. COMMUN., vol. 264, 1999, pages 561 - 567, XP008158204
See also references of EP 2561869A4
ELSON, M. ET AL., COSMET. DERMATOL., vol. 8, 1995, pages 25 - 27
ELSON, M. ET AL., COSMET. DERMATOL., vol. 12, 1999, pages 32 - 34
ICHIKAWA ET AL., J. BIOL. CHEM., vol. 281, no. 25, 2006, pages 16927 - 34
ICHIKAWA ET AL., J. MOL. ENDOCRINOL., vol. 39, 2007, pages 239 - 47
SATO ET AL., BIOCHIM. BIOPHYS. ACTA, vol. 1622, 2003, pages 145 - 150
VITAMIN, vol. 80, no. 4, 2006, pages 203, XP008158244
IDE, Y. ET AL.: "Inhibition of matrix metalloproteinase expression by menatetrenone, a vitamin K2 analogue", ONCOL. REP., vol. 22, 2009, pages 599 - 604, XP008158201
BOND, M. ET AL.: "Nuclear factor kB activity is essential for matrix metalloproteinase-1 and -3 upregulation in rabit dermal fibroblasts", BIOCHEM. BIOPHYS. RES. COMMUN., vol. 264, 1999, pages 561 - 567, XP008158204
See also references of EP 2561869A4
ELSON, M. ET AL., COSMET. DERMATOL., vol. 8, 1995, pages 25 - 27
ELSON, M. ET AL., COSMET. DERMATOL., vol. 12, 1999, pages 32 - 34
ICHIKAWA ET AL., J. BIOL. CHEM., vol. 281, no. 25, 2006, pages 16927 - 34
ICHIKAWA ET AL., J. MOL. ENDOCRINOL., vol. 39, 2007, pages 239 - 47
SATO ET AL., BIOCHIM. BIOPHYS. ACTA, vol. 1622, 2003, pages 145 - 150
Attorney, Agent or Firm:
NAKAJIMA SHINSUKE (JP)
Shinsuke Nakajima (JP)
Shinsuke Nakajima (JP)
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