Title:
SKIN LIGHTENING COMPOSITIONS
Document Type and Number:
WIPO Patent Application WO1995023780
Kind Code:
A3
Abstract:
This invention relates to compositions, compounds, and methods for lightening skin, using active compounds having the general structure:wherein each X is halo; m is 1 to 4; each R' and R'' is independently selected from hydrogen, halo, C1-C10 alkyl, substituted C1-C10 alkyl, substituted or unsubstituted phenyl, substituted or unsubstituted naphthyl, OR, OCOR, OCRROR, COR, CR(OR)OR, CONRR, COOR, CRROR, CN, SR, and NRR; each R is selected from hydrogen, C1-C10 alkyl, substituted C1-C10 alkyl, substituted or unsubstituted phenyl, and substituted or unsubstituted naphthyl; n is 1 to 5; Z is O; in an amount effective to lighten skin; and a pharmaceutically-acceptable carrier therefor.
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Inventors:
KVALNES KALLA LYNN
DELONG MITCHELL ANTHONY
BRADBURY BARTON JAMES
MOTLEY CURTIS BOBBY
CARTER JOHN DAVID
DELONG MITCHELL ANTHONY
BRADBURY BARTON JAMES
MOTLEY CURTIS BOBBY
CARTER JOHN DAVID
Application Number:
PCT/US1995/002809
Publication Date:
September 28, 1995
Filing Date:
March 01, 1995
Export Citation:
Assignee:
PROCTER & GAMBLE (US)
International Classes:
A61K8/00; A61K8/11; A61K8/33; A61K8/34; A61K8/368; A61K8/30; A61K8/37; A61K8/41; A61K8/42; A61K8/44; A61K8/46; A61K8/49; A61K8/55; A61Q17/04; A61Q19/00; A61Q19/02; C07C41/48; C07C41/54; C07C43/315; C07D307/20; C07D309/10; C07D309/12; C07D333/32; C07D335/02; (IPC1-7): C07C43/315; A61K7/48; C07D307/20; C07D309/12; C07D335/02
Foreign References:
| EP0524109A1 | 1993-01-20 | |||
| FR2577805A1 | 1986-08-29 |
Other References:
PATENT ABSTRACTS OF JAPAN vol. 12, no. 209 (C - 504)<3056> 15 June 1988 (1988-06-15)
PATENT ABSTRACTS OF JAPAN vol. 11, no. 297 (C - 448)<2744> 25 September 1987 (1987-09-25)
M. SHIRAISHI ET AL: "Quinones. Part 3.", JOURNAL OF THE CHEMICAL SOCIETY, PERKIN TRANSACTIONS 1., 1983, LETCHWORTH GB, pages 1591 - 1599
B. J. LUDWIG ET AL: "Synthesis of beta-(4-hydroxy-2-methylphenoxy)-lactic acid, a metabolite of mephenesin", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 77, 5 November 1955 (1955-11-05), WASHINGTON, DC US, pages 5751 - 5753
B. EISTERT ET AL: "Versuche mit 2.6-Dimethoxy- und 2.3.5.6-Tetrahalogenbenzoquinonen", ANNALEN DER CHEMIE, vol. 735, 1970, WEINHEIM, pages 145 - 157
"Chemical Abstracts Service Registry Handbook, Number Section", AMERICAN CHEMICAL SOCIETY
PATENT ABSTRACTS OF JAPAN vol. 18, no. 542 (C - 1261)<6882> 17 October 1994 (1994-10-17)
PATENT ABSTRACTS OF JAPAN vol. 11, no. 297 (C - 448)<2744> 25 September 1987 (1987-09-25)
M. SHIRAISHI ET AL: "Quinones. Part 3.", JOURNAL OF THE CHEMICAL SOCIETY, PERKIN TRANSACTIONS 1., 1983, LETCHWORTH GB, pages 1591 - 1599
B. J. LUDWIG ET AL: "Synthesis of beta-(4-hydroxy-2-methylphenoxy)-lactic acid, a metabolite of mephenesin", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 77, 5 November 1955 (1955-11-05), WASHINGTON, DC US, pages 5751 - 5753
B. EISTERT ET AL: "Versuche mit 2.6-Dimethoxy- und 2.3.5.6-Tetrahalogenbenzoquinonen", ANNALEN DER CHEMIE, vol. 735, 1970, WEINHEIM, pages 145 - 157
"Chemical Abstracts Service Registry Handbook, Number Section", AMERICAN CHEMICAL SOCIETY
PATENT ABSTRACTS OF JAPAN vol. 18, no. 542 (C - 1261)<6882> 17 October 1994 (1994-10-17)
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