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Patent Searching and Data


Title:
SKIN-PROTECTION COMPOSITION CONTAINING DENDROBIUM-BASED INGREDIENTS
Document Type and Number:
WIPO Patent Application WO/2018/090805
Kind Code:
A1
Abstract:
A skin-whitening and skin-protection composition that comprises stilbenoid (s) and/or stilbenoid-containing extract (s) obtained from Dendrobium plants, such as Dendrobium officinale and Dendrobium nobile for the management of melanogenesis, skin-darkening and skin-aging. More particularly, it relates to the usage of Dendrobium ingredients and stilbenoids to reduce the formation of melanin in melanocytes. It also relates to the usage of Dendrobium ingredients and stilbenoids to reduce the generation of reactive oxygen species and oxidative free radicals. The use of Dendrobium-derived extracts or ingredients or stilbenoids in the formulation of skin-protection, skin-whitening and/or anti-skin aging products. Compounds for use in preparation of a composition for treating, preventing, and/or delaying the progress of skin darkening or for use in skin-whitening and skin-protection which are synthesized from dihydro-resveratrol and the related synthesis method are also provided.

Inventors:
ZHANG HONGJIE (CN)
TSANG SIU WAI (CN)
ZHU YU (CN)
Application Number:
PCT/CN2017/107798
Publication Date:
May 24, 2018
Filing Date:
October 26, 2017
Export Citation:
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Assignee:
UNIV HONG KONG BAPTIST UNIV (CN)
International Classes:
C07C69/80; A61K8/37
Foreign References:
CN102816090A2012-12-12
CN102369223A2012-03-07
CN106256349A2016-12-28
Other References:
VENERA CARDILE ET AL.: "Chemo-enzymatic synthesis and cell -growth inhibition activity of resveratrol analogues", BIOORGANIC CHEMISTRY, vol. 33, no. 1, 28 February 2005 (2005-02-28), pages 29, XP004720666, ISSN: 0045-2068, DOI: doi:10.1016/j.bioorg.2004.08.003
DIANA C.RUEDA ET AL.: "Identification of dihydrostilbenes in Pholidota chinensis as a new scaffold for GABAA receptor modulators", BIOORGANIC & MEDICINAL CHEMISTRY, vol. 22, no. 4, 15 February 2014 (2014-02-15), pages 1276 - 1284, XP028606351, ISSN: 0968-0896
Attorney, Agent or Firm:
DHC IP ATTORNEYS (CN)
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